Master projects 2021-2022
COMPUTATIONAL GENOMICS
| Supervisor's name | Institution | Group | Project's Title |
|---|---|---|---|
| Albert Jordan | IBMB-CSIC | Chromatin regulation of human and viral gene expression | Occupancy of histone H1 variants genome-wide and consequences of altering H1 levels on human chromatin organization and gene expression. |
| Alexandre Perera Lluna | Exheus SL | Bioinformatics Department | Development and validation of predictive models for the analysis of transcriptomic data based on artificial intelligence. |
| Amelie Baud | CRG | Amelie Baud | Dissecting the genetic basis of handling-induced micturition in BXD recombinant inbred mice |
| Anthony Mathelier | Centre for Molecular Medicine Norway, University of Oslo | Computational Biology & Gene Regulation / Mathelier Group | PREDICTING MASTER REGULATORS DISCRIMINATING BREAST CANCER SUBTYPES FROM RNA-SEQ DATA |
| Anthony Mathelier | Centre for Molecular Medicine Norway, University of Oslo | Computational Biology & Gene Regulation / Mathelier Group | PREDICTING EVOLUTIONARY CONSERVED PRIMARY MICRORNA TRANSCRIPTION START SITES ACROSS SPECIES |
| Anthony Mathelier and Vipin Kumar | Centre for Molecular Medicine Norway, University of Oslo | Computational Biology & Gene Regulation / Mathelier group | Identification of positively selected breast cancer somatic variants in 3D |
| Antonio Julià | Vall Hebron Institut de Recerca | Grup de Recerca en Reumatologia | Single-cell RNA-seq study of Juvenile Idiopathic Arthritis |
| Arnau Sebe-Pedros | Centre for Genomic Regulation (CRG) | Single-cell genomics and evolution | Investigating animal cell type diversity, evolution and regulation using single cell genomics and epigenomics approaches |
| Biola M. Javierre | Josep Carreras Leukaemia Research Institute | 3D Chromatin Organization | Deciphering the role and regulation of spatial-temporal genome architecture in B cells and diffuse large B cell lymphomas |
| Bolognesi Benedetta | IBEC | Phase Transitions in Health and Disease | Mapping Amyloid Nucleation by Deep Mutagenesis |
| Camille Lassale | IMIM | Cardiovascular Epidemiology and Genetics (PI: Roberto Elosua) | Diet quality, DNA methylation and transcriptomics: an integrated translational approach |
| Chaysavanh Manichanh | FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DERECERCA | Microbiome Lab | Development of bioinformatics and statistical tools to integrate meta-omics data to decipher the human microbiome |
| David Comas | UPF | Human Genome Diversity | Analysis of the human genome diversity: unravelling demographic and genomic processes |
| Donate Weghorn | Centre for Genomic Regulation (CRG) | Evolutionary Processes Modeling | Selection on cancer genomes exerted by the immune system |
| Eulàlia de Nadal | IRB Barcelona | Cell Signaling | Unraveling the intrinsic determinants of dynamic gene expression variability |
| Geòrgia Escaramís | Dpt. Ciències Biomèdiques, Universitat de Barcelona | Genòmica Funcional de Malalties Neurodegeneratives | Small-RNAs in neurodegenerative diseases: identification of deregulated species as potential biomarkers and therapeutic targets |
| Geòrgia Escaramís | Dpt. Ciències Biomèdiques, Universitat de Barcelona | Genòmica Funcional de Malalties Neurodegeneratives | Exploring the small transcriptome (sRNAs) in neurodegenerative diseases |
| Iñaki Martin-Subero | IDIBAPS | Biomedical Epigenomics | Dissecting the single cell chromatin architecture of normal and neoplastic B-cells. |
| Javier del Campo | Institut de Biologia Evolutiva (CSIC-UPF) | del Campo Lab. Microbial Ecology and Evolution. | The Microeukaryotic Virome |
| Javier del Campo | Institut de Biologia Evolutiva (CSIC-UPF) | del Campo Lab. Microbial Ecology and Evolution | A Ribosomal Operon Reference Database |
| Javier del Campo | Institut de Biologia Evolutiva (CSIC-UPF) | del Campo Lab. Microbial Ecology and Evolution | The genomic mechanisms of ichthyocarbonates precipitaion |
| Jose A. Seoane | Vall d'Hebron Institute of Oncology (VHIO) | Cancer Computational Biology | Epigenetic role in aromatase inhibitor resistant breast cancer |
| Josefa Gonzalez | IBE (CSIC-UPF) | Evolutionary and Functional Genomics | Discovering new targets for malaria vector control strategies in urban settings |
| Josep F. Abril | Universitat de Barcelona | Computational Genomics Lab | Improving planarian interaction network with transcriptomes meta-analysis |
| Josep F. Abril | Universitat de Barcelona | Computational Genomics Lab | SARS-CoV-2 genomic analyses from metagenomic samples |
| Julio Rozas | Universitat de Barcelona | Evolutionary Genomics & Bioinformatics | Comparative and evolutionary analysis of multi-gene families in spider genomes |
| Lorenzo Pasquali | UPF | Endocrine Regulatory Genomics | Genetics and regulatory genomics of glucose metabolism diseases |
| Luis A Pérez Jurado & Carlos Ruiz Arenas | UPF | Genetics Unit | Combination of common and rare genetic variants to improve the diagnosis of complex disease |
| Mar Albà | Hospital del Mar Medical Research Institute (IMIM) | Genòmica Evolutiva | Identification of novel classes of neoantigens in cancer |
| Mar Albà | Hospital del Mar Medical Research Institute (IMIM) | Evolutionary Genomics | Using Nanopore RNA sequencing to explore the transcriptome |
| Marco Mariotti | Universitat de Barcelona | Comparative Genomics and Recoding lab | Computational genomics of proteins containing the special amino acid selenocysteine |
| Maria José Aranzana | IRTA-CRAG | Plant Genetics and Genomics | Machine learning methods in plant genomics |
| Mario Cáceres | Institut de Biotecnologia i de Biomedicina (IBB), UAB | Comparative and Functional Genomics Group | Functional and evolutionary impact of polymorphic inversions in the human genome |
| María Soler | Vall d'Hebron Research Institute (VHIR) | Psychiatry, Mental Health and Addiction | Polygenic and trasncriptomic risk score analyses in a sample of school children: assessing the effect of the genetic background of neurodevelopmental disorders on school performance |
| Michael Tress | CNIO | Biocomputing Group | Anotación de los genomas de humano y ratón |
| Núria López-Bigas | IRB Barcelona | Biomedical Genomics Group | Understanding cancer biology |
| Olivia Belbin | IIB-SantPau | Neurobiology of Dementias | A multimodal study to determine the polygenic risk for cognitive, structural and functional brain changes in Alzheimer's disease patients. |
| Ramiro Logares | Institute of Marine Sciences (CSIC) | log-lab and Ecology of Marine Microbes | The ocean microbiome: population dynamics and evolution in a changing planet |
| Ramon Massana | Institut de Ciències del Mar, CSIC | Ecology and Genomics of Marine Microbes | Unraveling the diversity and genomic data of marine microbial predators |
| Robert Castelo & Irene Madrigal | Universitat Pompeu Fabra / Hospital Clínic | Functional Genomics / Molecular Genetics | Deciphering genetics of hereditary hemorrhagic telangiectasia |
| Roderic Guigó | Center for Genomic Regulation | Bioinformatics and Genomics | Efficient gene annotation across the entire phylogenetic spectrum |
| Rory Johnson | University College Dublin | Laboratory for Genomics of Long Noncoding RNAs in Disease | Computational genomics of CRISPR-Cas, noncoding RNAs and cancer |
| Silvia G. Acinas & Pablo Sanchez | Institute of Marine Science (ICM) CSIC | Ecology and Genomics of Marine Microbes | Revealing active prokaryotic genomes from the global Deep Ocean microbiome. |
| Silvia G. Acinas & Felipe Hernandes Coutinho | Institute of Marine Sciences (ICM), CSIC | Ecology and Genomics of Marine Microbes | Revealing novel viruses among sentinel polar prokaryotes by single cell genome analyses |
| marta melé | Barcelona Supercomputing Center | transcriptomics and functional genomics lab | Understanding human individual variation in splicing |
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COMPUTATIONAL SYSTEMS BIOLOGY
| Supervisor's name | Institution | Group | Project's Title |
|---|---|---|---|
| Alfonso Valencia, Davide Cirillo & Jon Sánchez | Barcelona Supercomputing Center | Computational Biology | Graph-based approaches for the study of drug interactions in comorbidity relations |
| Alfonso Valencia, Davide Cirillo & Jon Sánchez | Barcelona Supercomputing Center | Computational Biology | Generation of age- and gender-dependent temporal disease trajectories from the Catalan population |
| Ana I. Caño-Delgado | CRAG (Centre for Research in Agricultural Genomics) | Brassinosteroid signaling in plant development | Development and implementation of bioinformatic tools for the functional analysis of plant adaptation to climate change |
| Anaïs Baudot | Marseille Medical Genetics | Network and Systems Biology for Diseases | Defining the molecular landscape of premature aging disease through biological networks |
| Andrés Ozaita | UPF | Laboratory of Neuropharmacology | Intellectual disability can be caused by genetic mutations |
| Arnau Montagud, Miguel Ponce de León, Alfonso Valencia | Barcelona Supercomputing Center (BSC) | Computational Biology | Use of data-tailored multiscale models to study drug transport |
| BEJANIN Alexandre | Research Institute of the Hospital de la Santa Creu i Sant Pau | Sant Pau Memory Unit | Neuroimaging of vascular disease in sporadic and genetic Alzheimer’s disease |
| Josep Vilardell | ICREA / IBMB | RNA Splicing | A Genomics Perspective of pre-mRNA Splicing |
| Josep Vilardell | ICREA / IBMB | pre-mRNA splicing | Splicing Systems Biology |
| Julio Alonso Padilla | Instituto de Salud Global de Barcelona | Iniciativa Chagas | Image analysis for setting up an anti-Trypanosoma cruzi biological assay |
| Marta Mele | Barcelona Supercomputing Center | Transcriptomics and Functional Genomics Lab | Unraveling the role of long non-coding RNAs in response to Ebola infection |
| Marta Melé | Barcelona Supercomputing Center | Transcriptomics and Functional Genomics Lab | Single-cell transcriptomic analysis across individuals |
| Mireia Valles-Colomer | CIBIO (University of Trento) | Segata Lab | The neuroactive potential of the underexplored fraction of the human microbiome and its association with health and disease |
| Pia Cosma | CRG | Reprogramming and Regeneration | Identification of master regulators of reprogramming |
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PHARMACOINFORMATICS & SYSTEMS PHARMACOLOGY
| Supervisor's name | Institution | Group | Project's Title |
|---|---|---|---|
| Patrick Aloy | Institute for Research in Biomedicine (IRB Barcelona) | Structural Bioinformatics & Network Biology | Formatting Biological Big Data to Enable Systems Pharmacology |
STRUCTURAL BIOINFORMATICS
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WEB DEVELOPMENT & BIOINFORMATICS TOOLS
| Supervisor's name | Institution | Group | Project's Title |
|---|---|---|---|
| Concepción Padilla | Sant Pau Hospital | Alzheimer Down Unit | "Stretching out the boundaries of the neuropsychological evaluation of dementia in Down's syndrome: a smartphone application for the evaluation of Alzheimer's disease in Down's syndrome". |
| Gianni De Fabritiis (UPF& Acellera) | Company: Acellera Labs | Acellera Labs | Machine learning in computational structural biology and drug discovery |
| Gianni De Fabritiis (UPF&Acellera) | Company: Acellera Labs | Company: Acellera Labs | Development of frontend capabilities and graphic user interface (GUI) for PlayMolecule.org |
| Javier del Campo | Institut de Biologia evolutiva (CSIC-UPF) | del Campo Lab. Microbial Ecology and Evolution | Shiny Tree |
| Lauro Sumoy | Institut Germans Trias i Pujol (IGTP) | High Content Genomics and Bioinformatics (HCGB) | Development of new modules in NGS analysis pipelines |
| Marc Güell | UPF | Translational Synthetic Biology | Computational approaches for precise engineering of human genomes |
| Marco Mariotti | Universitat de Barcelona | Comparative Genomics and Recoding lab | Building Treedex, an interactive framework for visualization and analysis of ‘omics data from multiple species |
| Osnat Hakimi | UIC/BSC | DEBBIE research group | Information extraction from biomaterials text using machine learning |
| Salvador Capella Gutierrez | Barcelona Supercomputing Center (BSC) | INB Coordination Node | Uplifting trimAl for handling thousands of sequences |
| Santiago Marco | IBEC | Signal and Information Processing for Sensing Systems | Comparison of workflows for the analysis of LCMS data in R |
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