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CARMONA , MERCE

MERCE CARMONA
Department of Medicine and Life Sciences (MELIS)
Scientific Officer
  • 1989-1991: Graduate in Scientific Officer in the School “Escola Bonanova” of Barcelona
  • 1991  “Mútua de Terrassa”
  • 1991-1993: “Hospital de la Santa Creu i Sant Pau” supported by a research grant.
  • 1994-2001: Scientific Officer at “Institut de Recerca Oncológica”
  • 2001-present: Scientific Officer at Universitat Pompeu Fabra, Barcelona, Spain.

PUBLICATIONS

Montañés, J.C., Huertas, M., Moro, S.G., Blevins, W.R., Carmona, M., Ayté, J., Hidalgo, E. and Albà, M.M. (2022) Native RNA sequencing in fission yeast reveals frequent alternative splicing isoforms. Genome Res. 32:1215-1227.

Salat-Canela, C., Carmona, M., Martín-García, R., Pérez, P., Ayté, J. Hidalgo, E. (2021) Stress-dependent inhibition of polarized cell growth through unbalancing the GEF/GAP regulation of Cdc42. Cell Rep. 37:109951.

Carmona, M., de Cubas, L., Bautista, E., Moral-Blanch, M., Medrano-Fernández, I., Sitia, R., Boronat, S., Ayté, J. and Hidalgo, E. (2019) Monitoring cytosolic H2O2 fluctuations from altered plasma membrane gradients or from mitochondrial activity. Nat. Commun. 10:4526.

Sánchez-Mir, L., Salat-Canela, C., Paulo, E., Carmona, M., Ayté, J., Oliva, B. and Hidalgo E. (2018). Phospho-mimicking Atf1 mutants bypass the transcription activating function of the MAP kinase Sty1 of fission yeast. Curr. Genet. 64:97-102.

Salat-Canela, C., Paulo, E., Sánchez-Mir, L., Carmona, M., Ayté, J., Oliva, B. and Hidalgo E. (2017). Deciphering the role of the signal- and Sty1 kinase-dependent phosphorylation of the stress-responsive transcription factor Atf1 on gene activation. J. Biol. Chem. 292:13635-13644.

Boronat, S., Domènech, A., Carmona, M., García-Santamarina, S., Bañó, M.C., Ayté, J. and Hidalgo, E. (2017). Lack of a peroxiredoxin suppresses the lethality of cells devoid of electron donors by channelling electrons to oxidized ribonucleotide reductase.  PLoS Genet. 13(6):e1006858.

Encinar del Dedo, J., Gabrielli, N., Carmona, M., Ayté, J., and Hidalgo, E. (2015) A cascade of iron-containing proteins governs the genetic iron starvation response to promote iron uptake and inhibit iron storage in fission yeast.  PLoS Genet. 11(3):e1005106.

Paulo, E., García-Santamarina, S., Calvo, I.A., Carmona, M., Boronat, S., Domènech, A., Ayté, J. and Hidalgo, E. (2014) A genetic approach to study H2O2 scavenging in fission yeast - distinct roles of peroxiredoxin and catalase.  Mol. Microbiol. 92:246-257.

Boronat, S., Domènech, A., Paulo, E., Calvo, I.A., García-Santamarina, S., García, P., Encinar del Dedo, J., Barcons, A., Serrano, E., Carmona, M. and Hidalgo, E.  (2014) Thiol-based H2O2 signalling in microbial systems.  Redox Biol. 2:395-399. 

Molero, C., Petrényi, K., González, A., Carmona, M., Gelis, S., Abrie, A., Strauss, E., Ramos, J., Dombradi, V., Hidalgo, E. and Ariño, J. (2013) The Schizosaccharomyces pombe fusion gene hal3 encodes three distinct activities.  Mol. Microbiol. 90:367-382.

Fernández-Vázquez, J., Vargas-Pérez, I., Sansó, M., Buhne, K., Carmona, M., Paulo, E., Hermand, D., Rodríguez-Gabriel, M., Ayté, J., Leidel, S. and Hidalgo, E. (2013) Modification of tRNA Lys UUU by Elongator is essential for efficient translation of stress mRNAs. PLoS Genet. 9(7):e1003647

Zuin, A., Carmona, M., Morales-Ivorra, I., Gabrielli, N., Vivancos, A.P., Ayté, J. and Hidalgo, E. (2010) Life-span extension by calorie restriction relies on the Sty1 MAP kinase stress pathway. EMBO J. 29:981-991.

González-Barca, E., Fernández de Sevilla, A., Domingo-Claros, A., Romagosa, V., Martín-Henao, G.A., De Sanjose, S., Carmona, M., Petit, J., García, J. and Grañena, A. (200) Autologous stem cell transplantation (ASCT) vith immunologically purged progenitor cells in patients vith advanced stage follicular lymphoma after early partial or complete remission: toxicity, follow-up of minimal residual disease and survival. Bone Marrow Transplant 26:1051-1056.

Martín-Henao, G.A., Picón, M., Limón, A., Carmona, M., Amill, B., Azqueta, C., López, R., González-Barca, E., Grañena, A., Brunet, S. and García, J. (1999) Immunomagnetic bone marrow (BM) and peripherical blood progenitor cell (PBPC) purging in follicular lymphoma (FL). Bone Marrow Transplant 23:579-587.

Servitje, O., Limón, A., Blanco, A., Carmona, M., Serrano, T., Romagosa, V., Gallardo, F., Gracia, J. and Peyri, J. (1999) Cardiac involvement and molecular stating in fatal case of mycosis fungoides.  Br J Dematol 1999, 141:531-535.

Curcó, N., Servitje, O., Llucià, M., Bertrán, J., Limón, A., Carmona, M. and Peyri, J. (1997) Informative use of PCR amplification of the TCRg  gene for early detection of cutaneous T cell lymphoma. A comparative study with Southern blot analysis. Br J Dermatol 137:673-679.

Pétriz, J., O’Connor, J., Carmona, M. and García-López, J. (1997) Is rhodamine 123 an appropiate fluorescent probe to assess P-glycoprotein mediated multidrug resistance in vinblastine-resistant CHO cells? Anal Cell Pat 14:129-140. 
  
Limón, A., Briones, J., Puig, T., Carmona, M., Fornas, O., Cancelas, J.A., Nadal, M., García, J., Rueda, F. and Barquinero, J. (1997) High titer retroviral vectors containing the enhanced green fluorescent protein (EGFP) gene for efficient expression in hematopoietic cells. Blood 90:3316-3321.

Limón, A.,  Bertrán, J., Llucià, M., Carmona, M., Canals, C., Ortega, J.J., García, J. and Rueda, F. (1995) Presentation of a PCR-nuclease protection strategy for minimal residual disease monitoring in B-ALL. Leukemia 9: 656-661, 1995.