Atrás Pastor Maeso, Manuel


Departamento de Medicina y Ciencias de la Vida
Informática Biomédica

Personal profile in our Scientific Output Portal (PPC)  

Biography note

Manuel Pastor is associate professor of biostatistics at the Universitat Pompeu Fabra (UPF, Spain) and head of the PharmacoInformatics group of the IMIM-UPF joint Research Programme on Biomedical Informatics (GRIB). He obtained a degree in Pharmacy in 1987 and a PhD in 1994 at the University of Alcalá (Spain). He spent a two years post-doctoral stay at the Laboratory of Chemometics, University of Perugia (Italy), under the supervision of Sergio Clementi and Gabriele Cruciani. As a post-doctoral researcher he worked first at the Laboratory of Molecular Pharmacology, University of Alcalá, under the supervision of Federico Gago and then as Scientific Leader for Multivariate Infometric Analysis Srl. in Perugia, between 1998 and 2000. Manuel is author of more than 50 scientific articles and book chapters and main responsible of numerous research projects in the field of drug design, in collaboration with public and private institutions. He developed numerous scientific software of widespread use in pharmaceutical companies and academic centers (GOLPE, ALMOND, Greater, SHOP, Pentacle)

Research lines

  • To improve current methodologies used for in silico prediction systems and multi-level modeling, at different areas related with drug discovery and development.
  • Application of structural and simulation methods to the investigation of the molecular mechanisms involved in the pharmacological effects of antipsychotic drugs.

Manuel participates in diverse international, EU funded projects (eg. Link3D, Cancergrid, eTOX, OpenPHACTS) in collaboration with pharmaceutical companies and academic institutions, aiming to improved the current state-of-the-art of drug design and development.