RECENT PUBLICATIONS

 

  • Hoijman E. , Fargas L., Bladet P and Alsina B  (2017). Pioneer neurog1 expressing cells ingress into the otic epithelium and instruct neuronal specification. eLife pii:e25543 Epub ahead of print

 

  • Alsina B and Whitfield TT (2017). Sculpting the labyrinth: Morphogenesis of the developing inner ear. Sem Cell Dev Biol 65:47-59. 

 

  • Streit A and Alsina B (2016). Morphogenetic Mechanisms of Inner ear Development. 235-258. Springer Book. Organogenetic Gene Networks, Editors Bovolenta P and Castelli-Gair J.  ISBN 978-3-319-42765-2

 

  • Pujadas G, Cervantes S, Tutusaus A, Ejarque M, Sanchez L, Garcia A, Esteban Y, Fargas L, Alsina B, Hartmann C, Gomis R, Gasa R (2016). Wnt9a deficiency discloses a repressive role of Tcf7l2 on endocrine differentiation in the embryonic pancreas. Sci Rep6:19223. DOI: 10.1038/srep19223.

 

  • Hoijman E, and Alsina B (2015). Cavity Morphogenesis: imaging mitotic forces in action. Cell Cycle 14(18):2867-8. DOI: 10.1080/15384101.2015.1076657. 

 

  • Rubbini D, Robert-Moreno A, Hoijman E, and Alsina B (2015). Retinoic Acid Signaling Mediates Hair Cell Regeneration by Repressing p27kip and Sox2 in Supporting Cells. Journal of Neurosc. 35 (47):15752-66. DOI 10.1523/JNEUROSCI. 1099.2015.

 

  • Hoijman E, Rubbini D, Colombelli J, and Alsina B (2015). Mitotic cell rounding and epithelial thinning regulate lumen growth and shape. Nature Commun 6:7355 DOI 10.1038

 

  • Iturbide A, Pascual-Reguant L,Fargas L, Cebrià JP, Alsina B, García de Herreros A, and Peiró S (2015).  LOXL2 oxidizes methylated TAF10 and controls TFIID-dependent genes during neural progenitor differentiation. Mol Cell 58(5):755-66. doi: 10.1016/j.molcel.2015.04.012.

 

  • Radosevic M, Fargas L and Alsina B (2014). The role of her4 in inner ear development and its relationship with proneural genes and Notch signalling. PLoS One, 9(10):e109860. doi: 10.1371

 

  • Maier EC, Saxena A, Alsina B, Bronner ME, Whitfield TT (2014). Sensational placodes: Neurogenesis in the otic and olfactory systems. Dev Biol 126(Pt 1):53-9. 

 

  • Mora N, Almudi I, Alsina B, Corominas M, Serras F (2012). The ss-amyloid protein precursor like (Appl) is a Ras1/MAPK regulated gene required for axonal targeting in Drosophila photoreceptor neurons. J Cell Sci. 2012 Nov 23. 

 

  • Radosevic M, Robert-Moreno A, Coolen M, Bally-Cuif L and Alsina B (2011). Her9, a zebrafish Hes1 ortholog, represses neurogenic fate in the inner ear downstream of Tbx1 and RA. Development 138(3):397-408.

 

  • Robert-Moreno A, Naranjo S, de la Calle-Mustienes E, Gómez-Skarmeta JL, Alsina B. (2010). Characterization of new otic enhancers of the pou3f4 gene reveal distinct signaling pathway regulation and spatio-temporal patterns. PLoS One. 5(12):e15907.

 

  • Naranjo S., Voesenek K., de la Calle-Mustienes E., Robert-Moreno A., Kokotas H., Grigoriadou M., Economides J., Van Camp G., Hilgert N., Moreno F., Alsina B., Petersen M., Kremer H. , Gomez-Skarmeta, JL. (2010). Multiple enhancers located in a 1 Mb region upstream of POU3F4 promote expression during inner ear development and may be required for hearing. Human Genetics 128(4):411-9.

 

  • Abelló B, Khatri S., Scotting P., Giráldez F., Alsina B. (2010). Independent regulation of Sox3 and Lmx1b by FGF and BMP signaling gradients determines the neurogenic and non-neurogenic domains in the otic placode. Dev Biol. 339(1):166-78.

Projects Projects

 
Cómo se forma el oído interno: genes, neuronas y forma 3D. ALSINA ESPAÑOL, BERTA (IP). BFU2014-53203-P. MINISTERIO DE ECONOMÍA Y COMPETITIVIDAD (MINECO) 2015 - 2017
Grup de Recerca en Biologia del Desenvolupament. GIRÁLDEZ ORGAZ, FERNANDO (IP). 2014 SGR 16. AGENCIA GESTIO AJUTS UNIVERSITARIS I RECERCA 2014 - 2016
Estudio in vivo y epigenético del papel del ácido retinoico en la regeneración de las células ciliadas. ALSINA ESPAÑOL, BERTA (IP). PR02012. FUNDACIÓN RAMÓN ARECES 2012 - 2014
Control espacio-temporal de la neurogenesis en el oído interno. ALSINA ESPAÑOL, BERTA (IP). BFU2011-27006. MINISTERIO DE CIENCIA E INNOVACIÓN (MICINN) 2012 - 2014
Organization Workshop Frontiers in Sensory Development. EMBO 2011 - 2011
Acción Complementaria Realización Congreso Internacional Frontiers in Sensory Development. Ministerio de Ciencia e Innovación 2011 - 2011
Grup de Recerca en Biologia del Desenvolupament (BIODES). GIRÁLDEZ ORGAZ, FERNANDO (IP). 2009SGR238. Agència de Gestió d'Ajuts Universitaris i de Recerca 2009 - 2013
Papel de los genes SoxB1 en el desarrollo neurosensorial del oído interno. ALSINA ESPAÑOL, BERTA (IP). BFU2008-00714. Ministerio de Ciencia e Innovación 2009 - 2009
Role of Sox3 during early inner ear development. Royal British Society 2008 - 2009
"Especificación regional y celular en el oído interno de vertebrados: progenitores, genes y señales". ALSINA ESPAÑOL, BERTA (IP). BFU2005-0345. Ministerio de Ciencia y Tecnología 2006 - 2008