Our laboratory is interested in the regulation of cell renewal, tissue remodelling and the acquisition of specific cell fates in a spatio-temporal order during organogenesis. We focus on the development of the inner ear to understand the signals and cellular events that lead to the senses of hearing and balance. Which signals allow the precise pattern of sensory neurons and hair cells, are those re-used during regeneration, how gene regulation takes place in genes involved in hearig and balance

By combining high resolution imaging technologies with genetic, pharmacological and mechanical perturbations in zebrafish we can quantify dynamical cellular and molecular changes over tissues and manipulate them. We also use  human inner ear organoids to decipher the role of mutations in the development of inner ear cell types.

 

Research interests: regeneration, organogenesis, neural development, cell shape, cell communication, organ niche

Keywords: 4D imaging, transgenesis, gene manipualtion, transcriptomics, zebrafish, inner ear, sensory ganglia, crispr, organoids

 

For more information go to research or publications

 

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13.12.2017
PhD offer-2018
PhD offer-2018
08.10.2018
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Berta Alsina
 

Department of Experimental and Health Sciences

Edifici PRBB (campus del Mar)
Doctor Aiguader, 88
08003 Barcelona

 (+34) 933160837

[email protected]