We integrate nanomaterials and quantitative biology to enable diagnostics and therapies, turning physicochemical design into predictive, measurable, and actionable biomedical outcomes.

Three scientific questions drive our work:

Q1. Predictive nano-bio interface.

How can we turn nanomaterial physicochemical properties into predictive rules for cellular interactions and downstream responses, so nanomedicines become safer-by-design and more reliably translatable?

Q2. Quantitative intracellular chemistry.

Can we measure dynamic intracellular biomarkers quantitatively, multiplexed, and non-destructively, and link them to phenotype using robust modelling (chemometrics / data-driven models)?

Q3. Triggerable, targeted theranostics (sense-and-actuate).

How do we engineer targeted nanosystems that perform on-demand actions (release, photothermal/photodynamic, ROS control) in hard-to-treat disease contexts, and validate efficacy, clearance, and safety in vivo?