Yu-Lee LY, Yu G, Lee YC, Lin SC, Pan J, Pan T, Yu KJ, Liu B, Creighton CJ, Rodriguez-Canales J, Villalobos PA, Wistuba II, de Nadal E, Posas F, Gallick GE, Lin SH. Osteoblast-secreted factors mediate dormancy of metastatic prostate cancer in the bone via activation of the TGFβRIII-p38MAPK-pS249/T252RB pathway. Cancer Res. 2018 Mar 7. pii: canres.1051.2017. doi: 10.1158/0008-5472.CAN-17-1051. [Epub ahead of print]

Duch A, Canal B, Barroso SI, García-Rubio M, Seisenbacher G, Aguilera A, de Nadal E, Posas F. Multiple signaling kinases target Mrc1 to prevent genomic instability triggered by transcription-replication conflicts. Nat Commun. 2018 Jan 25;9(1):379.
 

Vázquez-Ibarra A, Subirana L, Ongay-Larios L, Kawasaki L, Rojas-Ortega E, Rodríguez-González M, de Nadal E, Posas F, Coria R. Activation of the Hog1 MAPK by the Ssk2/Ssk22 MAP3Ks, in the absence of the osmosensors, is not sufficient to trigger osmostress adaptation in Saccharomyces cerevisiae. FEBS J. 2018 Jan 17. doi: 10.1111/febs.14385. [Epub ahead of print]

Silva A, Cavero S, Begley V, Solé C, Böttcher R, Chávez S, Posas F, de Nadal E. Regulation of transcription elongation in response to osmostress. PLoS Genet. 2017 Nov 20;13(11).

Chang YL, Tseng SF, Huang YC, Shen ZJ, Hsu PH, Hsieh MH, Yang CW, Tognetti S, Canal B, Subirana L, Wang CW, Chen HT, Lin CY, Posas F, Teng SC. Yeast Cip1 is activated by environmental stress to inhibit Cdk1-G1 cyclins via Mcm1 and Msn2/4. Nat Commun. 2017 Jul 4;8(1):56

Stojanovski K, Ferrar T, Benisty H, Uschner F, Delgado J, Jimenez J, Solé C, de Nadal E, Klipp E, Posas F, Serrano L, Kiel C. Interaction Dynamics Determine Signaling and Output Pathway ResponsesCell Rep. 2017 Apr 4;19(1):136-149.

Joaquin M, de Nadal E, Posas F. An RB insensitive to CDK regulationMol Cell Oncol. 2016 Dec 14;4(1).

Raguz Nakic Z, Seisenbacher G, Posas F, Sauer U. Untargeted metabolomics unravels functionalities of phosphorylation sites in Saccharomyces cerevisiaeBMC Syst Biol. 2016 Nov 15;10(1):104.

Gubern A, Joaquin M, Marquès M, Maseres P, Garcia-Garcia J, Amat R, González-Nuñez D, Oliva B, Real FX, de Nadal E and Posas FThe N-terminal phosphorylation of RB by p38 bypasses its inactivation by CDKs and prevents proliferation in cancer cells. Mol. Cell. 64(1):25-36 (2016).

Studer RA, Rodriguez-Mias RA, Haas KM, Hsu JI, Viéitez C, Solé C, Swaney DL, Stanford LB, Liachko I, Böttcher R, Dunham MJ, de Nadal E, Posas F, Beltrao P and Villén J. Evolution of protein phosphorylation across 18 fungal species. Science. 354(6309):229-232 (2016).

Macia J, Manzoni R, Conde N, Urrios A, de Nadal E, Solé R, Posas F. Implementation of Complex Biological Logic Circuits Using Spatially Distributed Multicellular ConsortiaPLoS Comput Biol. 2016 Feb 1;12(2)

Nadal-Ribelles M, Solé C, Xu Z, Steinmetz LM, de Nadal E, Posas F. Control of Cdc28 CDK1 by a stress-induced lncRNA. Mol Cell.  53(4):549-61 (2014).

Duch A, Felipe-Abrio I, Barroso S, Yaakov G, García-Rubio M, Aguilera A, Nadal E, Posas F. Coordinated control of replication and transcription by a SAPK protects genomic integrity. Nature; 493(7430):116-9 (2013).

Pelet S, Rudolf F, Nadal-Ribelles M, de Nadal E, Posas F, Peter M. Transient activation of the HOG MAPK pathway regulates bimodal gene expression. Science 332(6030): 732-5 (2011).

Regot S, Macia J, Conde N, Peeters T, Kentaro F, Hohmann S., de Nadal E, Posas F, Solé R. Distributed Biological Computation with Multicellular Engineered Networks. Nature 469: 207-11 (2011).

Mas G., de Nadal E., Dechant R., de la Concepción M.L., Logie C., Jimeno-González S., Chávez S., Ammerer G., Posas F. Recruitment of a chromatin remodeling complex by the Hog1 MAP kinase to stress genes. EMBO J. 28: 326-36 (2009).

Zapater M., Sohrmann M., Peter M., Posas F., de Nadal E. Selective requirement for SAGA in Hog1-mediated gene expression depending on the severity of the external osmostress conditions. Mol. Cell. Biol. 11: 3900-10 (2007).

Proft M, Mas G, de Nadal E, Vendrell A, Noriega N, Struhl K, Posas F. The stress-activated Hog1 kinase is a selective transcriptional elongation factor for genes responding to osmotic stress. Mol Cell. 23: 241-50 (2006).

Clotet J, Escoté X, Adrover MA, Yaakov G, Garí E, Aldea M, de Nadal E, Posas F. Phosphorylation of Hsl1 by Hog1 leads to a G2 arrest essential for cell survival at high osmolarity. EMBO J. 25: 2338-46 (2006).

Escoté X, Zapater M, Clotet J, Posas F. Hog1 mediates cell-cycle arrest in G1 phase by the dual targeting of Sic1. Nat. Cell. Biol., 6: 997-1002 (2004).

de Nadal E., Zapater M., Alepuz P.M., Sumoy L., Mas G., Posas F. The Hog1 MAP kinase recruits the Rpd3 histone deacetylase to activate osmoresponsive genes. Nature 427: 370-4 (2004).

 

Complete publication list:

2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2007 2006 2005 2004 2003 2002 2001

 

2018

 
Urrios A, Gonzalez-Flo E, Canadell D, de Nadal E, Macia J, Posas F. Plug-and-Play Multicellular Circuits with Time-Dependent Dynamic Responses. ACS Synth Biol. 2018 Apr 2. doi: 10.1021/acssynbio.7b00463. [Epub ahead of print]
 
Yu-Lee LY, Yu G, Lee YC, Lin SC, Pan J, Pan T, Yu KJ, Liu B, Creighton CJ, Rodriguez-Canales J, Villalobos PA, Wistuba II, de Nadal E, Posas F, Gallick GE, Lin SH. Osteoblast-secreted factors mediate dormancy of metastatic prostate cancer in the bone via activation of the TGFβRIII-p38MAPK-pS249/T252RB pathway. Cancer Res. 2018 Mar 7. pii: canres.1051.2017. doi: 10.1158/0008-5472.CAN-17-1051. [Epub ahead of print]
 
Duch A, Canal B, Barroso SI, García-Rubio M, Seisenbacher G, Aguilera A, de Nadal E, Posas F. Multiple signaling kinases target Mrc1 to prevent genomic instability triggered by transcription-replication conflicts. Nat Commun. 2018 Jan 25;9(1):379.
 

Vázquez-Ibarra A, Subirana L, Ongay-Larios L, Kawasaki L, Rojas-Ortega E, Rodríguez-González M, de Nadal E, Posas F, Coria R. Activation of the Hog1 MAPK by the Ssk2/Ssk22 MAP3Ks, in the absence of the osmosensors, is not sufficient to trigger osmostress adaptation in Saccharomyces cerevisiae. FEBS J. 2018 Jan 17. doi: 10.1111/febs.14385. [Epub ahead of print]

Martins TS, Pereira C, Canadell D, Vilaça R, Teixeira V, Moradas-Ferreira P, de Nadal E, Posas F, Costa V. The Hog1p kinase regulates Aft1p transcription factor to control iron accumulation. Biochim Biophys Acta. 2018 Jan;1863(1):61-70.

 

2017

 

Silva A, Cavero S, Begley V, Solé C, Böttcher R, Chávez S, Posas F, de Nadal E. Regulation of transcription elongation in response to osmostress. PLoS Genet. 2017 Nov 20;13(11).

Chang YL, Tseng SF, Huang YC, Shen ZJ, Hsu PH, Hsieh MH, Yang CW, Tognetti S, Canal B, Subirana L, Wang CW, Chen HT, Lin CY, Posas F, Teng SC. Yeast Cip1 is activated by environmental stress to inhibit Cdk1-G1 cyclins via Mcm1 and Msn2/4. Nat Commun. 2017 Jul 4;8(1):56. doi: 10.1038/s41467-017-00080-y.

Linke C, Chasapi A, González-Novo A, AI Sawad I, Tognetti S, Klipp E, Loog M, Krobitsch S, Posas F, Xenarios I, Barberis M. A Clb/Cdk1-mediated regulation of Fkh2 synchronizes CLB expression in the budding yeast cell cycle. NPJ Syst Biol Appl. 2017 Mar 6; 2:7. doi: 10.1038/s41540-017-0008-1. eCollection 2017.

Stojanovski K, Ferrar T, Benisty H, Uschner F, Delgado J, Jimenez J, Solé C, de Nadal E, Klipp E, Posas F, Serrano L, Kiel C. Interaction Dynamics Determine Signaling and Output Pathway ResponsesCell Rep. 2017 Apr 4;19(1):136-149. doi: 10.1016/j.celrep.2017.03.029.

Rodríguez-González M, Kawasaki L, Velázquez-Zavala N, Domínguez-Martín E, Trejo-Medecigo A, Martagón N, Espinoza-Simón E, Vázquez-Ibarra A, Ongay-Larios L, Georgellis D, de Nadal E, Posas F, Coria R  Role of the Sln1-phosphorelay pathway in the response to hyperosmotic stress in the yeast Kluyveromyces lactis. Mol Microbiol. 2017 Jun;104(5):822-836. doi: 10.1111/mmi.13664. Epub 2017 Mar 28.

 

2016

 

Joaquin M, de Nadal E, Posas F. An RB insensitive to CDK regulation. Mol Cell Oncol. 2016 Dec 14;4(1):e1268242. doi: 10.1080/23723556.2016.1268242. eCollection 2017.

.Raguz Nakic Z, Seisenbacher G, Posas F, Sauer U. Untargeted metabolomics unravels functionalities of phosphorylation sites in Saccharomyces cerevisiae. BMC Syst Biol. 2016. 10(1): 104.

Gubern A, Joaquin M, Marquès M, Maseres P, Garcia-Garcia J, Amat R, González-Nuñez D, Oliva B, Real FX, de Nadal E and Posas FThe N-terminal phosphorylation of RB by p38 bypasses its inactivation by CDKs and prevents proliferation in cancer cells. Mol. Cell. 2016. 64(1):25-36.

Studer RA, Rodriguez-Mias RA, Haas KM, Hsu JI, Viéitez C, Solé C, Swaney DL, Stanford LB, Liachko I, Böttcher R, Dunham MJ, de Nadal E, Posas F, Beltrao P and Villén J. Evolution of protein phosphorylation across 18 fungal species. Science. 2016. 354(6309):229-232.

Urrios A, Macia J, Manzoni R, Conde N, Bonforti A, de Nadal E, Posas F, Solé R. A Synthetic Mulicellular Memory DeviceACS Synth Biol. 2016 Aug 19;5(8):862-73. doi: 10.1021/acssynbio.5b00252

Urrios A, Parra-Cabrera C, Bhattacharjee N, Gonzalez-Suarez AM, Rigat-Brugarolas LG, Nallapatti U, Samitier J, DeForest CA, Posas F, Garcia-Cordero JL, Folch A. 3D-printing of transparent bio-microfluidic devices in PEG-DALab Chip. 2016 Jun 21;16(12):2287-94. doi: 10.1039/c6lc00153j. 10.1371/journal.pcbi.1004685. eCollection 2016 Feb.

Manzoni R, Urrios A, Velazquez-Garcia S, de Nadal E, Posas F. Synthetic biology: insights into biological computationIntegr Biol (Camb). 2016 Apr 18;8(4):518-32. doi: 10.1039/c5ib00274e

Macia J, Manzoni R, Conde N, Urrios A, de Nadal E, Solé R, Posas F. Implementation of Complex Biological Logic Circuits Using Spatially Distributed Multicellular Consortia. PLoS Comput Biol. 2016 Feb 1;12(2):e1004685. doi: 10.1371/journal.pcbi.1004685. eCollection 2016 Feb.

 

2015  

de Nadal E, Posas F. Osmostress-induced gene expression--a model to understand how stress-activated protein kinases (SAPKs) regulate transcription. FEBS J. 2015 Sep;282(17):3275-85. doi: 10.1111/febs.13323. Epub 2015 Jun 10. Review.

Solé C, Nadal-Ribelles M, Posas F, de Nadal E. A novel role for lncRNAs in cell cycle control during stress adaptation. Curr Genet. 2015 Aug 61(3):299-308.

Nadal-Ribelles M, Mas G, Millán-Zambrano G, Solé C, Ammerer G, Chávez S, Posas F, de Nadal E. H3K4 monomethylation dictates nucleosome dynamics and chromatin remodeling at stress-responsive genes. Nucleic Acids Res. 2015 Mar 26. pii: gkv220.

González-Novo A, Jiménez J, Clotet J, Nadal-Ribelles M, Cavero S, de Nadal E, Posas F. Hog1 Targets Whi5 and Msa1 Transcription Factors To Downregulate Cyclin Expression upon Stress. Mol Cell Biol. 2015 May 1;35(9):1606-18.

Sharifian H, Lampert F, Stojanovski K, Regot S, Vaga S, Buser R, Lee SS, Koeppl H, Posas F, Pelet S, Peter M. Parallel feedback loops control the basal activity of the HOG MAPK signaling cascade. Integr Biol (Camb). 2015 Apr 7

 

2014

Pauls E, Ruiz A, Badia R, Permanyer M, Gubern A, Riveira-Muñoz E, Torres-Torronteras J, ALvarez M, Mothe B, Brancer C, Crespo M, Menéndez-Arias, Clotet B, Keppler OT, Posas F, Ballana E Esté JA. Cell cycle control and HIV-1 susceptibility are linked by CDK6-dependent CDK2 phosphorylation of SAMHD1 in myeloid and lymphoid cells. J Immunol. 2014 Aug 15;193(4):1988-97

Nadal-Ribelles M, Solé C, Xu Z, Steinmetz LM, de Nadal E, Posas F. Control of Cdc28 CDK1 by stress-induced LncRNA.  Mol Cell. 2014 Feb 20;53(4): 546-61.

 

2013

Duch A, de Nadal E, Posas F. Dealing with transcriptional outburst during S phase to protect genomic integrity.  J Mol Biol. 2013 Nov 29;425(23):4745-55.

Geijer C, Medrala-Klein D, Petelenz-Kurdziel E, Ericsson A, Smedh M, Andersson M, Goksör M, Nadal-Ribelles M, Posas F, Krantz M, Nordlander B, Hohmann S. Initiation of the transcriptional response to hyperosmotic shock correlates with the potential for volume recovery. FEBS J. 2013 Aug 280(16):3854-67.

Regot S, de Nadal E, Rodríguez-Navarro S, González-Novo A, Pérez-Fernandez J, Gadal O, Seisenbacher G, Ammerer G, Posas F. The Hog1 Stress-activated Protein Kinase Targets Nucleoporins to Control mRNA Export upon Stress. J Biol Chem. 2013 Jun 14;288(24):17384-98.

Duch A, Felipe-Abrio I, Barroso S, Yaakov G, García-Rubio M, Aguilera A, de Nadal E and Posas F. Coordinated control of replication and transcription by a SAPK protects genomic integrity. Nature. 2013 Jan 3;493(7430):116-9.

 

2012

Nadal-Ribelles M, Conde N, Flores O, Gonzalez-Vallinas J, Eyras E, Orozco M, de Nadal E and Posas F. Hog1 bypasses stress-mediated down-regulation of transcription by RNA polymerase II redistribution and chromatin remodeling. Genome Biol. 2012 Nov 18;13(11):R106.

Saito H, Posas F.  Response to hyperosmotic stress. Genetics. 2012 Oct;192(2):289-318.

Ruiz-Roig C, Noriega N, Duch A, Posas F and de Nadal E. The Hog1 SAPK controls the Rtg1/Rtg3 transcriptional complex activity by multiple regulatory mechanisms. Mol Biol Cell. 2012 Sep 5.

Joaquin M, Gubern A and Posas F. A novel G1 checkpoint mediated by the p57 CDK inhibitor and p38 SAPK promotes cell survival upon stress. Cell Cycle. 2012 Aug 23;11(18).

Duch A, de Nadal and Posas F. The p38 and Hog1 SAPKs control cell cycle progression in response to environmental stresses. FEBS Lett. 2012 Aug 31;586(18):2925-31. Epub 2012 Jul 20.

Joaquin M, Gubern A, González-Nuñez D, Josué Ruiz E, Ferreiro I, de Nadal E, Nebreda AR and Posas F. The p57 CDKi integrates stress signals into cell-cycle progression to promote cell survival upon stress. EMBO J. 2012 May 8. doi: 10.1038/emboj.2012.122. 

Macía J, Posas F, Solé R. Distributed computation: the new wave of synthetic biology devices. Trends Biotechnol. 2012 Apr 17.

Barberis M, Linke C, Adrover MA, González-Novo A, Lehrach H, Krobitsch S, Posas F and Klipp E. Sic1 plays a role in timing and oscillatory behaviour of B-type cyclins. Biotechnol Adv. 2012 Jan;30(1):108-30. Epub 2011 Sep 18.

 

2011

Vendrell A and Posas F. Sir2 plays a key role in cell fate determination upon SAPK activation. Aging. 2011, 3 (12): 1163-8.

de Nadal E, Ammerer G, and Posas F. Controlling gene expression in response to stress. Nat Rev Genet. 2011 Nov 3. doi: 10.1038/nrg3055. 

de Nadal and Posas F. Elongating under stress. Genetics Research International. Volume 2011 (2011), Article ID 326286.

Adrover MA, Zi Z, Duch A, Schaber J, González-Novo A, Jimenez J, Nadal-Ribelles M, Clotet J, Klipp E and Posas F. Time-Dependent Quantitative Multicomponent Control of the G1-S Network by the Stress-Activated Protein Kinase Hog1 upon Osmostress. Sci Signal. 2011 Sep 27;4(192):ra63.

Vendrell A, Martínez-Pastor M, González-Novo A, Pascual-Ahuir A, Sinclair DA, Proft M and  Posas F. Sir2 histone deacetylase prevents programmed cell death caused by sustained activation of the Hog1 stress-activated protein kinase. EMBO Rep. 2011 Aug 12. doi: 10.1038/embor.2011.154.

Solé C, Nadal-Ribelles M, Kraft C, Peter M, Posas F and de Nadal E. Control of Ubp3 ubiquitin protease activity by the Hog1 SAPK modulates transcription upon osmostress. EMBO J. 2011 Jul 8;30(16):3274-84. 

Klein M, Morillas M, Vendrell A, Brive L, Gebbia M, Wallace IM, Giaever G, Nislow C, Posas F and Grøtli M. Design, Synthesis and Characterization of a Highly Effective Inhibitor for Analog-Sensitive (as) Kinases. PLoS One. 2011;6(6):e20789. Epub 2011 Jun 17.

Pelet S, Rudolf F, Nadal-Ribelles, de Nadal, Posas F and Peter M. Transient activation of the HOG MAPK pathway regulates bimodal gene expression. Science. 2011 May 6;332(6030):732-5. 

Regot S, Macia J, Conde N, Furukawa K, Kjellén T, Peeters T, Hohmann S, de Nadal, Posas F and Solé R. Distributed biological computation with multicellular engineered networks. Nature. 2011 Jan 13;469(7329):207-11.

 

2010

Ferreiro I, Barragan M, Gubern A, Ballestar E, Joaquin M and Posas F. The p38 SAPK is recruited to chromatin via its interaction with transcription factors. J Biol Chem. 2010 Oct 8;285(41):31819-28.

Warringer J, Hult M, Regot S, Posas F and Sunnerhagen P. The HOG Pathway Dictates the Short-term Translational Response after Hyperosmotic Shock. Mol Biol Cell. 2010 Sep 1;21(17):3080-92.

Schaber J, Adrover MA, Eriksson E, Pelet S, Petelenz-Kurdziel E, Klein D, Posas F, Goksör M, Peter M, Hohmann S and Klipp E. Biophysical properties of Saccharomyces cerevisae and their relationship with HOG pathway activation. Eur Biophys J. 2010 Oct 39 (11):1547-56.

Ruiz-Roig C, Viéitez C, Posas F and de Nadal E. The RPD3L HDAC complex is essential for the heat stress response in yeast. Mol Microbiol. 2010 May;76(4):1049-62. 

Ferreiro I, Joaquin M, Islam A, Gomez-Lopez G, Barragan M, Lombardía L, Domínguez O, Pisano DG, Lopez-Bigas N, Nebreda AR and Posas F. Whole genome analysis of p38 SAPK-mediated gene expression upon stress. BMC Genomics. 2010 11:144.

de Nadal E and Posas F. Multilayered control of gene expression by stress-activated protein kinases.  EMBO J.2010 29 (1):4-13.

 

2009

Klopf E, Paskova L, Solé C, Mas G, Petryshyn A, Posas F, Wintersberger U, Ammerer G, Schüller C. Cooperation between the INO80 complex and histone chaperones determines adaptation of stress gene transcription in the yeast Saccharomyces cerevisae.  Mol Cell Biol. 2009 Sep;29(18):4994-5007.

Yaakov G, Duch A, García-Rubio M, Clotet J, Jimenez J, Aguilera A and Posas F. The Stress-activated Protein Kinase Hog1 Mediates S-phase Delay in Response to Osmostress. Mol Biol Cell. 29 (18):4994-5007 (2009).

Macia J, Regot S, Peeters T, Conde N, Solé R  and Posas F. Dynamic Signaling in The Hog1 MAPK Pathway Relies on High Basal Signal.  Science Signaling. 2 (63):1-9 (2009).

Mas G, de Nadal E, Dechant R, Rodríguez de la Concepción ML, Logie C, Jimeno-González S, Chávez S, Ammerer G and Posas F. Recruitment of a chromatin remodelling complex by the Hog1 MAP kinase to stress genes.  EMBO J. 28 (4):326-336 (2009).

2007 

de Nadal E, Real FX and Posas F. Mucins, osmosensors in eukaryotic cells?. Trends Cell Biol. 17: 571-574 (2007).

Clotet J and Posas F. Control of cell cycle in response to osmostress: lessons from yeastMethods Enzymol. 428: 63-76 (2007).

Zapater M, Sohrmann M, Peter M, Posas F and de Nadal E. Selective requirement for SAGA in HOG1-mediated gene expression depending on the severity of the external osmostress conditions. Mol. Cell. Biol. 27(11): 3900-3910 (2007).

 

2006

Proft M, Mas G, de Nadal E, Vendrell A, Noriega N, Struhl K and Posas F. The stress-activated Hog1 kinase is a selective transcriptional elongation factor for genes responding to osmotic stress.  Molecular Cell. 23: 241-250 (2006). 

Clotet J, Escoté X , Adrover MA, Yaakov G, Gari E, Aldea M, de Nadal E and Posas F. Phosphorylation of Hsl1 by Hog1 leads to a G(2) arrest essential for cell survival at high osmolarity. EMBO J. 25 (11):2338-46 (2006).  

 

2005

Zapater M, Clotet J, Escoté X and Posas F. Control of cell cycle progression by the stress-activated Hog1 MAPK.  Cell Cycle. 2005 Jan; 4(1):6-7.

 

2004   

Escoté X, Zapater M, Clotet J and Posas F. Hog1 mediates cell-cycle arrest in G1 phase by the dual targeting of Sic1. Nat. Cell. Biol. 6 (10): 997-1002 (2004). 

Tomás-Cobos L, Casadomé L, Mas G, Sanz P and Posas F. Expression of the HXT1 low affinity glucose transporter requires the coordinated activities of the HOG and glucose signalling pathways.  J Biol Chem. 2004 May 21; 279(21):22010-9.

de Nadal E, Zapater M, Alepuz PM, Sumoy L, Mas G and Posas F. The Hog1 MAP kinase recruits the Rpd3 histone deacetylase to activate osmoresponsive genesNature. 427 (6972): 370-374 (2004). 

 

2003

Alepuz PM, De Nadal E, Zapater M, Ammerer G and Posas F. Osmostress-induced transcription by Hot1 depends on a Hog1-mediated recruitment of the RNA Pol II.  EMBO J. 22: 2433-2442 (2003).

de Nadal E, Casadomé L and Posas F. Targeting the MEF2-Like Transcription Factor Smp1 by the Stress-Activated Hog1 Mitogen-Activated Protein Kinase.  Mol. Cell. Biol. 23: 229-37 (2003). 

 

2002

de Nadal E, Alepuz PM and Posas F. Dealing with osmostress through MAP Kinase activationEMBO Rep. 3: 735-740 (2002). 

 

2001

Proft M, Pascual-Ahuir A, de Nadal E, Ariño J, Serrano R and Posas F. Regulation of the Sko1 transcriptional repressor by the Hog1 MAP kinase in response to osmotic stress.  EMBO J. 20: 1123-1133 (2001).