Publications (since 2000)

Campanario S, Ramírez-Pardo I, Hong X, Isern J, Muñoz-Cánoves P. Assessing Autophagy in Muscle Stem Cells. Front Cell Dev Biol. 2021 Jan 21;8:620409.

Dell'Orso S, Juan AH, Moiseeva V, García-Prat L, Muñoz-Cánoves P, Sartorelli V. Protocol for RNA-seq library preparation starting from a rare muscle stem cell population or a limited number of mouse embryonic stem cells. STAR Protoc. 2021 Apr 15;2(2):100451.

Serrano AL, Muñoz-Cánoves P. Mouse Models of Muscle Fibrosis. Methods Mol Biol. 2021;2299:357-370.

Potapov I, García-Prat L, Ravichandran S, Muñoz-Cánoves P, Del Sol A. Computational modelling of stem cell-niche interactions facilitates discovery of strategies to enhance tissue regeneration and counteract ageing. FEBS J. 2021 Mar 22.

Nicolás-Ávila JA, Lechuga-Vieco AV, Esteban-Martínez L, Sánchez-Díaz M, Díaz-García E, Santiago DJ, Rubio-Ponce A, Li JL, Balachander A, Quintana JA, Martínez-de-Mena R, Castejón-Vega B, Pun-García A, Través PG, Bonzón-Kulichenko E, García-Marqués F, Cussó L, A-González N, González-Guerra A, Roche-Molina M, Martin-Salamanca S, Crainiciuc G, Guzmán G, Larrazabal J, Herrero-Galán E, Alegre-Cebollada J, Lemke G, Rothlin CV, Jimenez-Borreguero LJ, Reyes G, Castrillo A, Desco M, Muñoz-Cánoves P, Ibáñez B, Torres M, Ng LG, Priori SG, Bueno H, Vázquez J, Cordero MD, Bernal JA, Enríquez JA, Hidalgo A. A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart. Cell. 2020 Oct 1;183(1):94-109.e23.

García-Prat L, Perdiguero E, Alonso-Martín S, Dell’Orso S, Ravichandran K, Brooks SR, Juan AH, Campanario S, Jiang K, Hong X, Ortet L, Moiseeva V, Rebollo E, Sun H-W, Musarò A, Sandri M, del Sol A, Sartorelli V, Muñoz-Cánoves P. FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age. Nature Cell Biology 22:1307, 2020

Sreenivasan K, Ianni A, Künne C, Strilic B, Günther S, Perdiguero E, Krüger M, Spuler S, Offermanns S, Gómez-Del Arco P, Redondo JM, Muñoz-Cánoves P, Kim J, Braun T. Attenuated Epigenetic Suppression of Muscle Stem Cell Necroptosis Is Required for Efficient Regeneration of Dystrophic Muscles. Cell Reports 31:107652, 2020

Nicolás-Ávila JA, Lechuga-Vieco AV, Esteban-Martínez L, …., Muñoz-Cánoves P, Ibáñez B, Torres M, Ng LG, Priori SG, Bueno H, Vázquez J, Cordero MD, Bernal JA, Enríquez JA, Hidalgo A. A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart. Cell 183:94, 2020

González-Hernández S, Gómez MJ, Sanchez-Cabo F, Méndez-Ferrer S, Muñoz-Cánoves P, Isern J. Sox17 Controls Emergence and Remodeling of Nestin-Expressing Coronary Vessels. Circulation Research 127:e252, 2020

Segalés J, Perdiguero R, Serrano AL, Sousa-Victor P, Ortet L, Jardi M, Budanov A, Garcia-Prat L, Sandri M, David M. Thomson DM, Karin M, Lee JH, Muñoz-Cánoves P. Sestrin prevents atrophy of disused and aging muscles by integrating anabolic and catabolic signals. Nature Communications 11:189, 2020

Sousa-Victor P, Neves J, Muñoz-Cánoves P. Muscle stem cell aging: identifying ways to induce tissue rejuvenation. Mech Ageing Dev. 188:111246, 2020

Iavarone F, Guardiola O, Scagliola A, Andolfi GSerrano A, Perdiguero E, Brunelli S, Muñoz-Cánoves P, Minchiotti G. Cripto shapes macrophage plasticity and restricts EndMT in injured and diseased skeletal muscle. EMBO Reports. 21: e49075, 2020

Muñoz-Cánoves P, Neves J, Sousa-Victor P. Understanding muscle regenerative decline with aging: new approaches to bring back youthfulness to aged stem cells. FEBS J. 287: 406, 2020

Perdiguero E, Moiseeva V, Muñoz-Cánoves P. Simultaneous Isolation of Stem and Niche Cells of Skeletal Muscle: Applicability for Aging Studies. Methods Mol Biol. 2045:13, 2019

Muñoz-Cánoves P, Huch M. Definitions for adult stem cells debated. Nature 563:328-329, 2018

Sousa-Victor P, García-Prat L, Muñoz-Cánoves P. New mechanisms driving muscle stem cell regenerative decline with aging. Int J Dev Biol. 62:583, 2018

Baar MP, Perdiguero E, Muñoz-Cánoves P, de Keizer PL. Musculoskeletal senescence: a moving target ready to be eliminated. Curr Opin Pharmacol. 40:147-155, 2018

Chang NC, Sincennes MC, Chevalier FP, Brun CE, Lacaria M, Segalés J, Muñoz-Cánoves P, Ming H, Rudnicki MA. The Dystrophin Glycoprotein Complex Regulates the Epigenetic Activation of Muscle Stem Cell Commitment. Cell Stem Cell. 5:755-768, 2018.

Solanas G, Peixoto FO, Perdiguero E, Jardí M, Ruiz-Bonilla V, Datta D, Symeonidi A, Castellanos A, Welz PS, Caballero JM, Sassone-Corsi P, Muñoz-Cánoves P*, Benitah SA*. Aged Stem Cells Reprogram Their Daily Rhythmic Functions to Adapt to Stress. Cell 170:678-692, 2017  (* co-corresponding)

Perdiguero E, Serrano AL, Muñoz-Cánoves P. Cilia Control Fat Deposition during Tissue Repair. Dev Cell 42:114-116, 2017

Testoni G, Duran J, García-Rocha M, Vilaplana F, Serrano AL, Sebastián D, López-Soldado I, Sullivan MA, Slebe F, Vilaseca M, Muñoz-Cánoves P, Guinovart JJ.  Lack of Glycogenin Causes Glycogen Accumulation and Muscle Function Impairment. Cell Metab. 26:256-266, 2017

López-Luppo M, Catita J, Ramos D, Navarro M, Carretero A, Mendes-Jorge L, Muñoz-Cánoves P, Rodriguez-Baeza A, Nacher V, Ruberte J. Cellular Senescence Is Associated With Human Retinal Microaneurysm Formation During Aging. Invest Ophthalmol Vis Sci. 58:2832-2842, 2017

García-Prat L, Sousa-Victor P, Muñoz-Cánoves P. Proteostatic and Metabolic Control of Stemness. Cell Stem Cell 20:593-608, 2017

Romero-Moya D, Santos-Ocaña C, Castaño J, Garrabou G, Rodríguez-Gómez JA, Ruiz-Bonilla V, Bueno C, González-Rodríguez P, Giorgetti A, Perdiguero E, Prieto C, Moren-Nuñez C, Fernández-Ayala DJ, Victoria Cascajo M, Velasco I, Canals JM, Montero R, Yubero D, Jou C, López-Barneo J, Cardellach F, Muñoz-Cánoves P, Artuch R, Navas P, Menendez P. Genetic Rescue of Mitochondrial and Skeletal Muscle Impairment in an Induced Pluripotent Stem Cells Model of Coenzyme Q10 Deficiency. Stem Cells 35:1687-1703, 2017

García-Prat L, Muñoz-Cánoves P, Martínez-Vicente M. Monitoring Autophagy in Muscle Stem Cells. Methods Mol Biol. 1556:255-280, 2017

Bengal E, Perdiguero E, Serrano AL, Muñoz-Cánoves P. Rejuvenating stem cells to restore muscle regeneration in aging. F1000Res. 6:76, 2017

Serrano AL, Muñoz-Cánoves P. Fibrosis development in early-onset muscular dystrophies: Mechanisms and translational implications. Semin Cell Dev Biol. 64:181-190, 2017

García-Prat L, Muñoz-Cánoves P. Aging, metabolism and stem cells: Spotlight on muscle stem cells. Mol Cell Endocrinol. 15;445:109-117, 2017

Segalés J, Perdiguero E, Muñoz-Cánoves P. Regulation of Muscle Stem Cell Functions: A Focus on the p38 MAPK Signaling Pathway. Front Cell Dev Biol. 2016

Medici D, Muñoz-Cánoves P, Yang PC, Brunelli S. Mesenchymal Transitions in Development. Stem Cells Int. 2016

García-Prat L, Muñoz-Cánoves P. Aging, metabolism and stem cells: Spotlight on muscle stem cells. Mol Cell Endocrinol. 2016

Pessina P, Muñoz-Cánoves P. Fibrosis-Inducing Strategies in Regenerating Dystrophic and Normal Skeletal Muscle. Methods Mol Biol. 2016

Sousa-Victor P, Muñoz-Cánoves P. Regenerative decline of stem cells in sarcopenia. Mol Aspects Med. 50:109-17, 2016

García-Prat L, Martínez-Vicente M, Muñoz-Cánoves P. Autophagy: a decisive process for stemness. Oncotarget (Autophagy and Cell Death section) 7:12286-8, 2016

García-Prat L, Muñoz-Cánoves P*, Martínez-Vicente M*. Dysfunctional autophagy is a driver of muscle stem cell functional decline with aging. Autophagy 12:612-3, 2016 (* co-corresponding)

García-Prat L, Martínez-Vicente M, Perdiguero E , Ortet L, Garcia-Ubreva J, Rebollo E, Ruiz-Bonilla V, Gutarra S, Ballestar E, Serrano AL, Sandri M, Muñoz-Cánoves P. Autophagy maintains stemness by preventing senescence. Nature 529: 37-42, 2016

Brack AS, Muñoz-Cánoves P. The ins and outs of muscle stem cell. Skel Muscle  2016.

Segalés J, Islam AB, Kumar R, Liu QC, Sousa-Victor P, Dilworth FJ, Ballestar E, Perdiguero E, Muñoz-Cánoves P. Chromatin-wide and transcriptome profiling integration uncovers p38α MAPK as a global regulator of skeletal muscle differentiation. Skelet Muscle. 2016

Gómez-Del Arco P, Perdiguero E, Yunes-Leites PS, Acín-Pérez R, Zeini M, Garcia-Gomez A, Sreenivasan K, Jiménez-Alcázar M, Segalés J, López-Maderuelo D, Ornés B, Jiménez-Borreguero LJ, D'Amato G, Enshell-Seijffers D, Morgan B, Georgopoulos K, Islam AB, Braun T, de la Pompa JL, Kim J, Enriquez JA, Ballestar E, Muñoz-Cánoves P, Redondo JM. The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle Identity and Metabolic Homeostasis. Cell Metab. 23:881-92, 2016

Muñoz-Cánoves P, Carvajal JJ, Lopez de Munain A, Izeta A. Editorial: Role of Stem Cells in Skeletal Muscle Development, Regeneration, Repair, Aging, and Disease. Front Aging Neurosci. 2016

García-Prat L, Martínez-Vicente M, Muñoz-Cánoves P. Methods for Mitochondria and Mitophagy Flux Analyses in Stem Cells of Resting and Regenerating Skeletal Muscle. Methods Mol Biol. 2016

Muñoz-Cánoves P, Di Croce L. Special issue on Epigenetics. FEBS J. 282:1569-70, 2015

Pessina P, Kharraz Y, Jardí M, Fukada SI. Serrano AL, Perdiguero E, Muñoz-Cánoves P. Fibrogenic cell plasticity blunts tissue regeneration and aggravates muscular dystrophy. Stem Cell Reports 4:1046-60, 2015

Artandi SE, Blau HM, de Haan G, Geiger H, Goodell MA, Jones L, Levine RL, Muñoz-Cánoves P, Rodewald HR, Wagers A, Wang ZQ, Yamashita Y. Stem Cells and Aging: What's Next?  Cell Stem Cell 16: 578-81, 2015

Segalés J, Perdiguero E, Muñoz-Cánoves P. Epigenetic control of adult skeletal muscle stem cell functions.  FEBS J. 282: 1571-1588, 2015

Aso E, Serrano AL, Muñoz-Cánoves P, Ferrer I. Fibrinogen-Derived γ377-395 Peptide Improves Cognitive Performance and Reduces Amyloid-β Deposition, without Altering Inflammation, in AβPP/PS1 Mice. J Alzheimers Disease. 47: 403-12, 2015  

Sousa-Victor P, García-Prat L, Serrano AL, Perdiguero E, Muñoz-Cánoves P. Muscle stem cell aging: regulation and rejuvenation. Trends Endocrinol Metab. 26:287-96, 2015

Muñoz-Cánoves P, Serrano AL. Macrophages decide between regeneration and fibrosis in muscle. Trends Endocrin and Metab. 26: 449-50, 2015

Sousa-Victor P, García-Prat L, Muñoz-Cánoves P. Dual mTORC1/C2 inhibitors: gerosuppressors with potential anti-aging effect. Oncotarget. 6:23052-23054, 2015

López-Arribillaga E, Rodilla V, Pellegrinet L, Guiu J, Iglesias M, Roman AC, Gutarra S, González S, Muñoz-Cánoves P, Fernández-Salguero P, Radtke F, Bigas A, Espinosa LL. Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch. Development. 2015

Sousa-Victor P, Perdiguero E, Muñoz-Cánoves P. Geroconversion of aged muscle stem cells under regenerative pressure Cell Cycle 13:20, 2014

Bouché M, Muñoz-Cánoves P, Rossi F, Coletti D. Inflammation in muscle repairnd aging. Biomed Res Int. 2014

Kharraz Y, Guerra J, Pessina P, Serrano AL, Muñoz-Cánoves P.  Understanding the process of fibrosis in Duchenne muscular dystrophy. BioMed Res Int. 2014

Pessina P, Cabrera D, Morales G, Riquelme C, J Gutiérrez C, Serrano AL, Brandan E, Muñoz-Cánoves P. Novel and optimized strategies for inducing fibrosis in vivo: focus on Duchenne Muscular Dystrophy. Skelet Muscle 25;4:7, 2014 

Sousa-Victor P, Gutarra S, García-Prat L, Rodriguez-Ubreva J, Ortet L, Ruiz-Bonilla V, Jardí M, Ballestar E, González S, Serrano AL, Perdiguero E, Muñoz-Cánoves P. Geriatric muscle stem cells switch reversible quiescence into senescence. Nature 506:316-21, 2014

Muñoz-Cánoves P, Michele D. Special issue: myogenesis: introduction. FEBS J. 280: 3979, 2013

Acuña MJ, Pessina P, Olguin H, Cabrera D, Vio CP, Bader M, Muñoz-Cánoves P, Santos RA, Cabello-Verrugio C, Brandan E. Restoration of muscle strength in dystrophic muscle by angiotensin-1-7 through inhibition of TGF-β signalling. Human Mol Genet. 23:1237-49, 2013

Sandri M, Barberi L, Bijlsma AY, Blaauw B, Dyar KA, Milan G, Mammucari C, Meskers CG, Pallafacchina G, Paoli A, Pion D, Roceri M, Romanello V, Serrano AL, Toniolo L, Larsson L, Maier AB, Muñoz-Cánoves P, Musarò A, Pende M, Reggiani C, Rizzuto R, Schiaffino S. Signalling pathways regulating muscle mass in ageing skeletal muscle. The role of the IGF1-Akt-mTOR-FoxO pathway. Biogerontology 14:303-23 2013

Muñoz-Cánoves P, Scheele C, Pedersen BK, Serrano AL. IL-6 myokine signaling in skeletal muscle: a double-edged sword? FEBS J. 2013

Kharraz Y, Guerra J, Mann CJ, Serrano AL, Muñoz-Cánoves P. Macrophage plasticity and the role of inflammation in skeletal muscle repair.  Mediators Inflam. 2013:491497, 2013

García-Prat  L, Sousa-Victor P,  Muñoz-Cánoves P. Functional dysregulation of stem cells during aging: a focus on skeletal muscle stem cells. FEBS J. 2013

Vidal B, Ardite E, Suelves M, Ruiz-Bonilla V, Janué A, Flick J, Degen JL, Serrano AL, Muñoz-Cánoves P. Amelioration of Duchenne muscular dystrophy in mdx mice by elimination of matrix-associated fibrin-driven inflammation coupled to the alphaMbeta2 leukocyte integrin receptor.  Human Mol Genet 21:1989-2004, 2012

Perdiguero E, Kharraz Y, Serrano AL, Muñoz-Cánoves P. MKP-1 coordinates ordered macrophage-phenotype transitions essential for stem cell-dependent tissue repair. Cell Cycle 11:877-86, 2012

Liu QC, Zha X, Faralli H, Yin H, Louis-Jeune C, Perdiguero E, Pranckeviciene E, Muñoz-Cánoves P, Rudnicki MA, Brand M, Perez-Iratxeta C, Dilworth FJ. Comparative expression profiling identifies differential roles for Myogenin and p38αMAPK signaling in myogenesis. J. Cell Biol.  4:386-97, 2012

Ardite E, Perdiguero E, Vidal E, Gutarra S, Serrano AL, Muñoz-Cánoves P. PAI-1-regulated miR-21 defines a novel age-associated fibrogenic pathway in muscular dystrophy. J. Cell Biol. 196:163-75, 2012

Sousa-Victor P, Muñoz-Cánoves P, Perdiguero E. Regulation of skeletal muscle stem cells through epigenetic mechanisms. Toxicol Mech Methods. 21(4):334-42, 2011

Serrano AL, Mann CJ, Vidal B, Ardite E, Perdiguero E, Muñoz-Cánoves P. Cellular and molecular mechanisms regulating fibrosis in skeletal muscle repair and disease. Curr Top Dev Biol. 96:167-201, 2011

Mann CJ, Perdiguero E, Kharraz Y, Aguilar S, Pessina P, Serrano AL, Muñoz-Cánoves P. Aberrant repair and fibrosis development in skeletal muscle. Skelet Muscle. 1:21, 2011

Perdiguero E, Sousa-Victor P, Ruiz-Bonilla V, Jardí M, Caelles C, Serrano AL, Muñoz-Cánoves P. p38/MKP-1-regulated AKT coordinates macrophage transitions and resolution of inflammation during tissue repair. J Cell Biol. 195:307-22, 2011

Serrano AL, Muñoz-Cánoves P. Regulation and dysregulation of fibrosis in skeletal muscle. Exp Cell Res. 316:3050-8, 2010

Cuadrado A, Corrado N, Perdiguero E, Lafarga V, Muñoz-Canoves P, Nebreda AR. Essential role of p18Hamlet/SRCAP-mediated histone H2A.Z chromatin incorporation in muscle differentiation. EMBO J. 29:2014-25, 2010

Perdiguero E, Sousa-Victor P, Ballestar E, Muñoz-Cánoves P. Epigenetic regulation of myogenesis. Epigenetics 4:541-50, 2009

Perdiguero E, Muñoz-Cánoves P. Volume on "SAPKs". Chapter by the Authors: Transcriptional regulation by the p38 MAPK signaling pathway in mammalian cells. Curr Top Genetics. 2008 (Posas F & Nebreda AR, Editors)

Vidal B, Serrano AL, Tjwa M, Suelves M, Ardite E, De Mori R, Baeza B, Martínez de Lagrán M, Ruiz-Bonilla V, Jardí M, Gherardi R; Degen J, Christov C, Dierssen M, Dewerchin M, Carmeliet P, Muñoz- Cánoves P. Fibrinogen drives dystrophic muscle fibrosis via a TGFb/alternative macrophage activation pathway. Genes & Dev, 22:1747-52, 2008

Ruiz-Bonilla V, Perdiguero E, Gresh L, Serrano AL, Sousa-Victor P, Jardí M, Wagner EF, Muñoz-Cánoves P. Efficient adult skeletal muscle regeneration in mice deficient in p38beta, p38gamma and p38delta MAP kinases. Cell Cycle.7:2208-14, 2008

Serrano AL, Baeza-Raja B, Perdiguero E, Jardí M, Muñoz-Cánoves P. Interleukin-6 is an essential regulator of satellite cell-mediated skeletal muscle hypertrophy. Cell Metab. 7:33-44, 2008

Serrano AL, Jardi M, Suelves M, Klotman PE, Munoz-Canoves P. HIV-1 transgenic expression in mice induces selective atrophy of fast-glycolytic skeletal muscle fibers. Front Biosci. 13:2797-805, 2008

Suelves M, Vidal B, Serrano AL, Tjwa M, Roma J, López-Alemany R, Luttun A, Martínez de Lagrán M, Díaz MA, Jardí M, Roig M, Dierssen M, Dewerchin M, Carmeliet P, Muñoz-Cánoves P. uPA deficiency exacerbates muscular dystrophy in mdx mice. J. Cell Biol. 178: 1039-51, 2007

Perdiguero E, Ruiz-Bonilla V, Serrano AL, Muñoz-Cánoves P. Genetic Deficiency of p38alpha Reveals its Critical Role in Myoblast Cell Cycle Exit: The p38alpha-JNK Connection. Cell Cycle 6: 1298-303, 2007

Perdiguero E, Ruiz-Bonilla V, Gresh L, Hui L, Ballestar E, Sousa-Victor P, Baeza-Raja B, Jardi M, Bosch-Comas A, Esteller M, Caelles C, Serrano AL, Wagner EF, Munoz-Canoves P. Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation. EMBO J. 26:1245-56, 2007

Lluis F, Perdiguero E, Nebreda AR, Muñoz-Cánoves P. Regulation of skeletal muscle gene expression by p38 MAP kinases. Trends Cell Biol. 16:36-44, 2006

Nagamine Y, Medcalf RL, Muñoz-Cánoves P. Transcriptional and posttranscriptional regulation of the plasminogen activator system. Thromb Haemost. 93:661-675, 2005

Suelves M, Vidal B, Ruíz V, Baeza-Raja B, Díaz-Ramos MA, Cuartas I, Lluís F, Parra M, Jardí M, López-Alemany R, Serrano A, Muñoz-Cánoves P. The plasminogen activation system in skeletal muscle regeneration: antagonistic roles of urokinase-type plasminogen activator (uPA) and its inhibitor (PAI-1) Front. Biosci. 10:2978-2985, 2005

Vidal B, Parra M, Jardi M, Saito S, Appella E, Muñoz-Cánoves P. The alkylating carcinogen N-methyl-N'-nitro-N-nitrosoguanidine activates the plasminogen activator inhibitor-1 gene through sequential phosphorylation of p53 by ATM and ATR kinases Thromb Haemost. 93: 584-91, 2005

Lluís F, Ballestar E, Suelves M, Esteller M, Muñoz-Cánoves P. E47 phosphorylation by p38 MAP kinase promotes MyoD/E47 association and muscle-specific gene transcription EMBO J. 24: 974-984, 2005

Lopez-Alemay R, Suelves M, Diaz-Ramos A, Vidal B, Muñoz-Cánoves P. Alpha-enolase plasminogen receptor in myogenesis Front. Biosci. 10: 30-36, 2005

Baeza-Raja B, Muñoz-Cánoves P. p38 MAPK-induced NF-kB activity is required for skeletal muscle differentiation. Mol. Biol. Cell. 15: 2013-2026, 2004

Suelves M., Lluis F, Ruiz V, Nebreda AR, Muñoz-Cánoves P. Phosphorylation of the transactivation domain of MRF4 by p38 MAPK mediates repression of specific myogenic genes. EMBO J. 33: 365-375, 2004

Figueroa A, Cuadrado A, Fan J, Atasoy L, Muscat GE, Muñoz-Cánoves P, Gorospe M, Muñoz A. Role of HuR in skeletal myogenesis through coordinate regulation of muscle differentiation genes. Mol. Cell. Biol. 23: 4991-5004, 2003

Lopez-Alemany R, Suelves M, Muñoz-Cánoves P. Plasmin generation dependent on α-enolase-type plasminogen receptor is required for myogenesis. Thromb Haemost. 90: 724-733, 2003

López-Alemany R, Redondo,JM, Nagamine Y, Muñoz-Cánoves P. Plasminogen activator inhibitor type-1 Inhibits insulin signaling by competing with avb3 integrin for vitronectin binding. Eur J Biochem 270: 814-821, 2003

Suelves M, López-Alemany R, Lluís F, Aniorte G, Serrano E, Parra M, Carmeliet P, Muñoz-Cánoves P. Plasmin activity is required for myogenesis in vitro and skeletal muscle regeneration in vivo. Blood 99: 2835-2844, 2002

Espinosa L, Santos S, Ingles-Esteve J, Muñoz-Cánoves P, Bigas A. p65-NFkappaB synergizes with Notch to activate transcription by triggering cytoplasmic translocation of the nuclear receptor corepressor N-CoR. J Cell Sci. 115: 1295-303, 2002

Lluís F, Roma J, Suelves M, Parra M, Aniorte G, Gallardo E, Illa I, Rodríguez L, Hughes SM, Carmeliet P, Roig M, Muñoz-Cánoves P. Urokinase-type plasminogen activator is required for skeletal muscle regeneration in vivo. Blood 97: 1703-1711, 2001

Ferrer I, Puig B, Goutan E, Gombau L, Muñoz-Cánoves P. Methylazoximethanol acetate-induced cell death in the granule cell layer of the developing cerebellum is associated with caspase-3 activation, but does not depend on the tissue-type plasminogen activator. Neuroscience Lett. 299: 77-80, 2001

Tzarfaty-Majar V, López-Alemany R, Feinstein Y, Gomabau L, Goldshmidt O, Soriano E, Muñoz-Cánoves P*, Klar A*. Plasmin-mediated release of the guidance molecule F-spondin from the extracellular matrix J. Biol. Chem. 276: 28233-28241, 2001 (*co-corresponding authors).

Parra M, Jardí, Koziczak M, Nagamine Y, Muñoz-Cánoves P. p53 phosphorylation at serine 15 is required for transcriptional induction of the plasminogen activator inhibitor- 1 (PAI-1) gene by the alkylating agent MNNG. J. Biol. Chem. 276: 36303-36310, 2001

Parra M, Lluis F, Miralles F, Caelles C, Muñoz-Cánoves P. The cJun N-terminal kinase (JNK) signaling pathway mediates induction of urokinase-type plasminogen activator (uPA) by the alkylating agent MNNG.Blood 96:1415-24, 2000.