Modelling of radio-frequency ablation in patient-specific left atria and effect on its electromechanics Modelling of radio-frequency ablation in patient-specific left atria and effect on its electromechanics

Radio-frequency ablation (RFA) in the left atria is a widely used treatment in patients with atrial fibrillation when drug therapy has failed. Nevertheless, due to the low thickness of the atria in some parts there is a high risk of wall perforation, especially when the same RFA catheter parameters are globally used, which is often the case. Modelling of RFA procedures with computational models can help to personalise the therapy settings in a local basis, allowing more power and duration in regions with larger wall thickness, being more cautious in thinner regions. The main goal of this project is to develop models of RFA ablation to work on patient-specific left atria obtained from CT images where wall thickness has been locally obtained. Complex geometry regions such as close to the pulmonary veins will be particularly studied, as well as the electromechanics effects of the ablation. This project will be performed in collaboration with electrophysiologists of the Teknon-Quirón centre.

Supervisor: Oscar Camara