Electrophysiological model of the left ventricle in the presence of heterogeneous scar to predict optimal ablation targets with Open-Source software Electrophysiological model of the left ventricle in the presence of heterogeneous scar to predict optimal ablation targets with Open-Source software

Finding the optimal ablation targets in radio-frequency ablation (RFA) therapies for ischemic ventricular tachycardia (VT) patients is not obvious. Clinicians in advanced centres combine pre-operative imaging information of tissue viability (e.g. MRI) with intra-operative electrophysiological data (e.g. electro-anatomical maps). Computational models and simulations have the potential to provide better insights to the clinician to which parts of the heterogeneous scar are prone to arrythmogenecity and thus reduce interventional times. The main goal of this project is to use the recently available Open Source electrophysiological solver, OpenCARP, to study which border zone channels of the scar need to be targeted in RFA procedures of VT patients. This project will be performed in collaboration with world-wide experts of VT at Teknon-Quirón Salud as well as with engineers of the ADAS3D company.


Supervisor: Oscar Camara