The Research Group on Single Cell Behavior is led by Dr. Lucas Carey. The group focuses on understanding how cell-to-cell variability in quantitative phenotypes is determined (such as the expression level of a gene or the growth rate of a cell and the underlying molecular mechanisms) and the evolutionary reasons why certain molecular mechanisms are used to produce a given quantitative phenotype.
The main research lines are:
- The relationship between regulatory architecture and noise in gene expressions.
- A molecular mechanism that allows cells to 'measure' their size.
- Nonlinearity in the relationship between gene expression and fitness.
- Co-evolution of quantitative traits due to environmental pressures.