The research group on Live-cell structural biology is focused on the quantitative characterisation of complex molecular processes that regulate cell growth, both from a mechanistic and structural point of view. The main target of their studies is vesicle trafficking, and their favorite model organism is the budding yeast. The group combines cell engineering, advanced light microscopy, biochemical approaches and data integration in silico to analyse the concerted action of protein complexes that build supra-assemblies. When needed, they develop new approaches to visualise those processes that could not be described before. The mechanistic insights are then extrapolated to physiological and pathological conditions.