CASCANTE SERRATOSA, MARTA

Coordinator of Computational Systems Biology


Full Professor of Biochemistry at the Universitat de Barcelona.

Member of the board of directors of Spanish Society of Biochemistry and Molecular Biology (SEBBM).

Member of the editorial board of "Metabolomics, of the Scientific Comitee of the Metabolomics Society Journal and of the "Systems Biology International Society" from its foundation.

She has a large experience in combining biochemistry, molecular and cell biology with systems biology to construct models for biomedical and clinical research and to predict the consequences of genetic, proteomic or metabolic interventions with special focus to multifactorial diseases.

Her research in the last five years has been mainly in the field of metabolomics and fluxomics with a focus to the development of tools and application to cancer and other multifactorial diseases.

She has more than 100 publications in the field of metabolomics, fluxomics and modeling biochemical networks and 15 years of experience in training PhD and post-doc students.

Moreover, as part of the UB Biomedical Institute (IBUB) and the IDIBAPS-Hospital Clinic translational research Institute she has a large experience in translational research projects.

In particular, she has been a team leader in 3 EU projects in this area in the last five years in the framework of FP6 and FP7 programmes and actually she is a partner in the FP7-Marie Curie Initial Training Network "METAFLUX" (Metabolic Flux Analysis and Cancer, 2011-2014).

Research lines

Her research group is working in the characterization of metabolic adaptations accompanying essential cell fates and pathological alterations associated with multifactorial diseases such as cancer.

Recently they have developed the software package Isodyn to evaluate distribution of metabolic fluxes in the cellular reaction network from metabolite's Cisotopomer obtained by mass spectrometry (MS) methods.

Isodyn is able to reveal altered metabolic pathways and differential metabolic flux distribution under diverse altered conditions