Seizure cycles in focal epilepsy

  • Authors
  • Leguia MG, Andrzejak RG, Rummel C, Fan JM, Mirro EA, Tcheng TK, Rao VR, Baud MO
  • UPF authors
  • ANDRZEJAK ., RALPH GREGOR;
  • Type
  • Scholarly articles
  • Journal títle
  • JAMA Neurology
  • Publication year
  • 2021
  • Pages
  • 0-0
  • ISSN
  • 2168-6149
  • Publication State
  • Published
  • Abstract
  • ). Across individuals, circadian seizure cycles showed 5 peaks: morning, mid-afternoon, evening, early night, and late night. Multidien cycles of IEA showed peak periodicities centered around 7, 15, 20, and 30 days. Independent of multidien period length, self-reported and electrographic seizures consistently occurred during the days-long rising phase of multidien cycles of IEA. CONCLUSIONS AND RELEVANCE Findings in this large cohort establish the high prevalence of plural seizure cycles and help explain the natural variability in seizure timing. The results have the potential to inform the scheduling of diagnostic studies, the delivery of time-varying therapies, and the design of clinical trials in epilepsy.
  • Complete citation
  • Leguia MG, Andrzejak RG, Rummel C, Fan JM, Mirro EA, Tcheng TK, Rao VR, Baud MO. Seizure cycles in focal epilepsy. JAMA Neurology 2021; ( ).
Bibliometric indicators
  • 10 times cited Scopus
  • 11 times cited WOS
  • Índex Scimago de 5.298 (2020)