Impact of Flow Dynamics on Device-Related Thrombosis After Left Atrial Appendage Occlusion

  • Authors
  • Mill J, Olivares AL, Arzamendi D, Agudelo V, Regueiro A, Camara O, Freixa X
  • UPF authors
  • MILL TENA, JORDI; OLIVARES MIYARES, ANDY LUIS; CAMARA REY, OSCAR; AGUDELO SUAREZ, ANDRES ALONSO;
  • Type
  • Scholarly articles
  • Journal títle
  • Canadian Journal of Cardiology
  • Publication year
  • 2020
  • Volume
  • 36
  • Number
  • 6
  • Pages
  • 0-0
  • ISSN
  • 0828-282X
  • Publication State
  • Published
  • Abstract
  • A 78-year-old man with atrial fibrillation (CHA 2DS 2VASc score of 3) and contraindication to oral anticoagulation owing to intracranial hemorrhage underwent successful left atrial appendage occlusion (LAAO) with a 22-mm Amplatzer Amulet. The patient was discharged on 2.5 mg/12 h apixaban without incidences. At 3 months, after ruling out device-related thrombosis (DRT) with transesophageal echocardiography (TEE), apixaban was stopped and aspirin started. A subsequent imaging control with TEE at 6 months (3 months after changing from apixaban to aspirin) detected the presence of DRT below the pulmonary ridge ( Fig. 1). Device thrombosis was successfully treated with 3 months of 2.5 mg/12 h apixaban, and aspirin was restarted. Unfortunately, 3 months later, TEE revealed DRT recurrence at the same level. This time, apixaban was maintained for 6 months. After this period, TEE showed no thrombus and aspirin treatment was restored. Six-month control TEE/angiographic computed tomography (angio-CT) showed a flat-tissue coverage of the ¿triangle-area¿ below the pulmonary-ridge with no clear image of thrombus .
  • Complete citation
  • Mill J, Olivares AL, Arzamendi D, Agudelo V, Regueiro A, Camara O, Freixa X. Impact of Flow Dynamics on Device-Related Thrombosis After Left Atrial Appendage Occlusion. Canadian Journal of Cardiology 2020; 36(6).
Bibliometric indicators
  • 7 times cited Scopus
  • 4 times cited WOS
  • Índex Scimago de 1.395(2020)