He studied Physics at the National University of Rosario. In 1987, he received his Ph.D. in Physics for his thesis on Relativistic Atomic Collisions. In 1997, he obtained his habilitation (maximal academical degree in Germany) in Computer Science at the Technical University of Munich for his thesis on Neural Learning. In 2001, he received his Ph.D. in Psychology at the Ludwig-Maximilian-University of Munich for his thesis on Visual Attention.

His research interests include computational neuroscience, neuropsychology, psycholinguistics, biological networks, statistical formulation of neural networks, and chaos theory. He has actively contributed to the modelling and integration of experimental measurements through theoretical frameworks, and collaborates with many experimentalists to confront theory and experiments. Recognised as a world leader in computational neuroscience, he has led pioneering work in dynamical modelling of human brain activity. He is an ERC Advanced grantee and member of the Human Brain Project.