List of results published directly linked with the projects co-funded by the Spanish Ministry of Economy and Competitiveness under the María de Maeztu Units of Excellence Program (MDM-2015-0502).

List of publications acknowledging the funding in Scopus.

The record for each publication will include access to postprints (following the Open Access policy of the program), as well as datasets and software used. Ongoing work with UPF Library and Informatics will improve the interface and automation of the retrieval of this information soon.

The MdM Strategic Research Program has its own community in Zenodo for material available in this repository   as well as at the UPF e-repository   

 

 

Back Raote I, Ortega Bellido M, Pirozzi M, Zhang C, Melville d, Parashuraman S, Zimmermann T, Malhotra V. TANGO1 assembles into rings around COPII coats at ER exit sites. Journal of Cell Biology

Raote I, Ortega Bellido M, Pirozzi M, Zhang C, Melville d, Parashuraman S, Zimmermann T, Malhotra V. TANGO1 assembles into rings around COPII coats at ER exit sites. Journal of Cell Biology Mar 2017, jcb.201608080; DOI: 10.1083/jcb.201608080

TANGO1 (transport and Golgi organization 1) interacts with CTAGE5 and COPII components Sec23/Sec24 and recruits ERGIC-53 (endoplasmic reticulum [ER]–Golgi intermediate compartment 53)–containing membranes to generate a mega-transport carrier for export of collagens and apolipoproteins from the ER. We now show that TANGO1, at the ER, assembles in a ring that encircles COPII components. The C-terminal, proline-rich domains of TANGO1 molecules in the ring are initially tilted onto COPII coats but appear to be pushed apart as the carrier grows. These findings lend support to our suggestion that growth of transport carriers for exporting bulky cargoes requires addition of membranes and not simply COPII-mediated accretion of a larger surface of ER. TANGO1 remains at the neck of the newly forming transport carrier, which grows in size by addition of ERGIC-53–containing membranes to generate a transport intermediate for the export of bulky collagens.