Calvo, I.A., García, P., Ayté, J. and Hidalgo, E. 2012. The transcription factors Pap1 and Prr1 collaborate to activate antioxidant, but not drug tolerance, genes in response to H2O2. Nucleic Acids Res. (in press)
Sansó, M., Vargas-Pérez, I., García, P., Ayté, J. and Hidalgo, E. 2011. Nuclear roles and regulation of chromatin structure by the stress-dependent MAP kinase Sty1 of Schizosaccharomyces pombe. Mol. Microbiol. 82:542-554
García-Santamarina, S., Boronat, S., Espadas, G., Ayté, J., Molina, H. and Hidalgo, E. 2011. The oxidized thiol proteome in fission yeast - optimization of an ICAT-based method to identify H2O2-oxidized proteins. J. Proteomics 74:2476-2486
Sansó, M., Vargas-Pérez, I., Quintales, L., Antequera, F., Ayté, J. and Hidalgo, E. 2011. Gcn5 facilitates Pol II progression, rather than recruitment to nucleosome-depleted stress promoters, in Schizosaccharomyces pombe. Nucleic Acids Res. 39:6369-6379
Ivanova, T., Gómez-Escoda, B., Hidalgo, E. and Ayté, J. 2011. G1/S transcription and the DNA-synthesis checkpoint: common regulatory mechanisms. Cell Cycle 10:912-915.
Gómez-Escoda, B., Ivanova, T., Calvo, I.A., Alves-Rodrigues, I., Hidalgo, E. and Ayté, J. 2011. Yox1 links MBF-dependent transcription to completion of DNA synthesis. EMBO Reports 12:84-89.
Zuin, A., Castellano-Esteve, D., Ayté, J and Hidalgo, E. 2010. Living on the edge: stress and activation of stress responses promote lifespan extension. Aging 2:231-237.
Zuin, A., Carmona, M., Morales-Ivorra, I., Gabrielli, N., Vivancos, A.P., Ayté, J. and Hidalgo, E. 2010. Life-span extension by calorie restriction relies on the Sty1 MAP kinase stress pathway. EMBO J. 29:981-991.
Calvo, I.A., Gabrielli, N., Iglesias-Baena, I., García-Santamarina, S., Hoe, K.L., Kim, D.U., Sansó, M., Zuin, A., Pérez, P., Ayté, J. and Hidalgo, E. 2009. Genome-wide screen of genes required for caffeine tolerance in fission yeast. PLoS ONE 4(8):e6619.
Moldón, A. and Ayté, J. 2009. At the (3') end, you'll turn to meiosis. Nat. Struct. Mol. Biol. 16:350-351.
Moldón, A., Malapeira, J., Gabrielli, N., Gogol, M., Gómez-Escoda, B., Ivanova, T., Seidel, C. and Ayté, J. 2008. Promoter-driven splicing regulation in fission yeast. Nature 455:997-1000.
Zuin, A., Calvo, I.A., Gabrielli, N., García-Santamaría, S., Hoe, K.-L., Kim, D.U., Park, H.-O., Hayles, J., Ayté, J. and Hidalgo, E. 2008. Mitochondrial dysfunction increases oxidative stress and decreases chronological life span in fission yeast. PLoS ONE 3(7):e2842.
Sansó, M., Gogol, M., Ayté, J., Seidel, C. and Hidalgo, E. 2008. The transcription factors Pcr1 and Atf1 have distinct roles in stress- and Sty1-dependent gene regulation. Eukaryot. Cell 7:826-835.
López-Avilés, S., Lambea, E., Moldón, A., Grande, M., Fajardo, A., Rodríguez-Gabriel, M.A., Hidalgo, E. and Aligué, R. 2008. Activation of Srk1 by the MAP kinase Sty1 precedes its dissociation from the kinase and signals its degradation. Mol. Biol. Cell 19:1670-1679.
Jara, M., Vivancos, A.P. and Hidalgo, E. 2008. C-terminal truncation of the peroxiredoxin Tpx1 decreases its sensitivity for hydrogen peroxide without compromising its role in signal transduction. Genes Cells 13:171-9.
Jara, M., Vivancos, A.P., Calvo, I.A., Moldón, A., Sansó, M. and Hidalgo, E. 2007. The peroxiredoxin Tpx1 is essential as a H2O2-scavenger during aerobic growth in fission yeast. Mol. Biol. Cell 18:2288-2295.
Vivancos, A.P., Jara, M., Zuin, A., Sansó, M. and Hidalgo, E. 2006. Oxidative stress in Schizosaccharomyces pombe: different H2O2 levels, different response pathways. Mol. Genet. Genomics 276:495-502.
Zuin, A., Vivancos, A.P., Sansó, M., Takatsume, Y., Ayté, J., Inoue, Y. and Hidalgo, E. 2005. The glycolytic metabolite methylglyoxal activates Pap1 and Sty1 stress responses in Schizosaccharomyces pombe. J. Biol. Chem. 280:36708-36713.
Vivancos, A. P., Castillo, E.A., Biteau, B., Nicot, C., Ayté, J., Toledano, M.B. and Hidalgo, E. 2005. A cysteine-sulfinic acid in peroxiredoxin regulates H2O2-sensing by the antioxidant Pap1 pathway. Proc. Nat. Acad. Sci. USA 101:8875-8880.
Malapeira, J., Moldón, A., Hidalgo, E., Smith, G.R., Nurse, P. and Ayté, J. 2005. A Meiosis-Specific Cyclin Regulated By Splicing Is Required For Proper Progression Through Meiosis. Mol. Cell Biol. 25:6330-6337.
Vivancos, A., Castillo, E.A., Jones, N., Ayte, J. and Hidalgo, E. 2004. Activation of the redox-sensor Pap1 by hydrogen peroxide requires modulation of the intracellular oxidant concentration. Mol. Microbiol. 52: 1427-1435.
Castillo, E.A., Vivancos, A.P., Ayté, J., Jones, N. and Hidalgo, E. 2003. Schizosaccharomyces pombe cells lacking the Ran-binding protein Hba1 show a multidrug resistance phenotype due to constitutive nuclear accumulation of Pap1. J. Biol. Chem. 278:40565-40572
Castillo, E.A., Ayté, J., Chiva, C., Moldón, A., Carrascal, M., Abián, J., Jones, N. and Hidalgo, E. 2002. Diethylmaleate activates the transcription factor Pap1 by covalent modification of critical cysteine residues. Mol. Microbiol. 45:243-254.
Ayté, J. Schweitzer, C., Zarzov, P., Nurse, P. and DeCaprio, J.A. 2001. Feedback regulation of the MBF transcription factor by cyclin Cig2. Nature Cell Biol. 3:1043-1050.