Publications

Jimenez-Guri, E and Pujades, C An ancient mechanism of hindbrain patterning has been conserved in vertebrate evolution. Evolution and Development, in press 2010

Jimenez-Guri, E, Udina, F, Colas, JF, Sharpe, J,  Padrón, L, Torres M, Pujades, C. Clonal analysis in mice underlines the importance of positional information during hindbrain segmentation. PLoS ONE 5(4): e10112. doi:10.1371/journal.pone.0010112, 2010

Sapède, D. and Pujades, C. Hedgehog signalling governs the development of sensory epithelium and its associated innervation in the zebrafish inner ear, J. Neurosc. 30: 3612-3623, 2010

Aragón, F. and Pujades, C. FGF signaling controls caudal hindbrain specification through Ras-ERK1/2 pathway, BMC Dev. Biol, 9:61, 2009

Alsina, B., Giraldez, F. and Pujades C. Patterning and cell fate in inner ear development. Review in Science in Hispania Special Issue, Int. J. Dev. Biol, Jan 23. [Epub ahead of print], 2009

Vázquez-Echeverría C, Dominguez-Frutos E, Charnay P, Schimmang T, Pujades C. Analysis of kreisler mutants reveals new roles of the hindbrain-derived signals in the establishment of the otic neurogenic domain. Dev. Biol., 322(1):167-78 2008

Bell D, Streit A, Gorospe I, Varela-Nieto I, Alsina B, Giraldez F. (2008). Spatial and temporal segregation of auditory and vestibular neurons in the otic placode. Dev. Biol. 322(1): 109-120.

Kamaid A and Giráldez F. (2008). Btg1 and Btg2 gene expression during early chick development. Dev. Dyn. 237(8):2158-2169.

Giraldez F, Fritzsch B. (2007). The molecular biology of ear development - "Twenty years are nothing". Int J Dev Biol. 51(6-7):429-38.

Abelló G, Alsina B. (2007). Establishment of a proneural field in the inner ear. Int J Dev Biol. 51(6-7):483-93.

Schneider-Maunoury S, Pujades C. (2007). Hindbrain signals in otic regionalization: walk on the wild side.Int J Dev Biol. 51(6-7):495-506.

Guimarães L, Domínguez-del-Toro E, Chatonnet F, Wrobel L, Pujades C, Monteiro LS, Champagnat J. (2007). Exposure to retinoic acid at the onset of hindbrain segmentation induces episodic breathing in mice. Eur J Neurosci. 25(12):3526-36.

Lecaudey V, Ulloa E, Anselme I, Stedman A, Schneider-Maunoury S, Pujades C. (2007). Role of the hindbrain in patterning the otic vesicle: a study of the zebrafish vhnf1 mutant. Dev Biol. 303(1):134-43.

Abelló G, Khatri S, Giráldez F, Alsina B. (2007). Early regionalization of the otic placode and its regulation by the Notch signaling pathway . Mech Dev. 124(7-8):631-45.

Neves J, Kamaid A, Alsina B, Giraldez F. (2007). Differential expression of Sox2 and Sox3 in neuronal and sensory progenitors of the developing inner ear of the chick . J Comp Neurol. 503(4):487-500.

Pujades C, Kamaid A, Alsina B, Giraldez F. (2006). BMP-signaling regulates the generation of hair-cells . Dev Biol. 292(1):55-67.

Aragón F, Vázquez-Echeverría C, Ulloa E, Reber M, Cereghini S, Alsina B, Giraldez F, Pujades C. (2005). vHnf1 regulates specification of caudal rhombomere identity in the chick hindbrain . Dev Dyn. 234(3):567-76.

Pellicer M, Giráldez F, Pumarola F, Barquinero J. (2005). Stem cells for the treatment of hearing loss . Acta Otorrinolaringol Esp. 56(6):227-32.

Alsina B, Abelló G, Ulloa E, Henrique D, Pujades C, Giraldez F. (2004). FGF signaling is required for determination of otic neuroblasts in the chick embryo . Dev Biol.267(1):119-34.

Alsina B, Giraldez F, Varela-Nieto I. (2003). Growth factors and early development of otic neurons: interactions between intrinsic and extrinsic signals . Curr Top Dev Biol. 57:177-206.

Camarero G, Leon Y, Gorospe I, De Pablo F, Alsina B, Giraldez F, Varela-Nieto I. (2003). Insulin-like growth factor 1 is required for survival of transit-amplifying neuroblasts and differentiation of otic neurons . Dev Biol. 262(2):242-53.

Mechta-Grigoriou F, Giudicelli F, Pujades C, Charnay P, Yaniv M. (2003). c-jun regulation and function in the developing hindbrain .Dev Biol. 258(2):419-31.

Pujades C, Guez-Guez B, Dunon D. (2002). Melanoma Cell Adhesion Molecule (MCAM) expression in the myogenic lineage during early chick embryonic development . Int J Dev Biol. 46(2):263-6.

Alsina B, Vu T, Cohen-Cory S. (2001).Visualizing synapse formation in arborizing optic axons in vivo: dynamics and modulation by BDNF . Nat Neurosci. 4(11):1093-101.

Frago LM, Camerero G, Cañón S, Pañeda C, Sanz C, Leon Y, Giraldez F, Varela-Nieto I. (2000). Role of diffusible and transcription factors in inner ear development: implications in regeneration . Histol Histopathol. 15(2):657-66.

Voiculescu O, Taillebourg E, Pujades C, Kress C, Buart S, Charnay P, Schneider-Maunoury S. (2001).Hindbrain patterning: Krox20 couples segmentation and specification of regional identity . Development. 128(24):4967-78.

Alais S, Allioli N, Pujades C, Duband JL, Vainio O, Imhof BA, Dunon D. (2001). HEMCAM/CD146 downregulates cell surface expression of beta1 integrins . J Cell Sci. 114(Pt 10):1847-59.

Vendrell V, Carnicero E, Giraldez F, Alonso MT, Schimmang T. (2000) Induction of inner ear fate by FGF3 . Development. 127(10):2011-9.

Sanz C, León Y, Cañón S, Alvarez L, Giraldez F, Varela-Nieto I. (1999). Pattern of expression of the jun family of transcription factors during the early development of the inner ear: implications in apoptosis . J Cell Sci. 112 (Pt 22):3967-74.

León Y, Sanz C, Frago LM, Camarero G, Cañón S, Varela-Nieto I, Giráldez F. (1999). Involvement of insulin-like growth factor-I in inner ear organogenesis and regeneration . Horm Metab Res. 31(2-3):126-32.

Helmbacher F, Pujades C, Desmarquet C, Frain M, Rijli FM, Chambon P, Charnay P. (1998). Hoxa1 and Krox-20 synergize to control the development of rhombomere 3 . Development. 125(23):4739-48.

Giraldez F. (1998).Regionalized organizing activity of the neural tube revealed by the regulation of lmx1 in the otic vesicle . Dev Biol. 203(1):189-200.

León Y, Sanz C, Giráldez F, Varela-Nieto I. (1998). Induction of cell growth by insulin and insulin-like growth factor-I is associated with Jun expression in the otic vesicle .J Comp Neurol. 398(3):323-32.

Torres M, Giráldez F. (1998). The development of the vertebrate inner ear . Mech Dev. 71(1-2):5-21

Garrido JJ, Alonso MT, Lim F, Carnicero E, Giraldez F, Schimmang T. (1998). Defining responsiveness of avian cochlear neurons to brain-derived neurotrophic factor and nerve growth factor by HSV-1-mediated gene transfer . J Neurochem. 70(6):2336-46.