The Biomedical Genomics lab at CEXS-UPF, headed by Núria López Bigas, has developed an innovative system for the analysis and integration of large amounts of cancer genomics data.
The results generated by this multidimensional resource called IntOGen are available for consultation on the website www.intogen.org. The February print edition of Nature Methods includes an article describing this new resource, and placing it at the disposal of the scientific commmunity: “IntOGen: Integration and data-mining of multidimensional oncogenomic data".
A platform for efficient management of information on cancer
IntOgen includes an efficient and intutitive web interface, and is designed to be
an essential tool for cancer research. There have been significant changes in cancer research in
recent years, with the incorporation of high performance technologies that enable the
identification of large amount
s of genomic alterations in tumour samples and cancerous cells.
The acumulation of large amounts of oncogenomic data, as well as the data generated by international projects such as “The Cancer Genome Atlas” and the “International Cancer Genome Consortium” have created a need for new strategies to examine, visualize and manage all this information in a biologically relevant way.
IntOGen is a new system that means that it is possible to compile, analyse and integrate data from genomic experiments studying various different types of alterations in different kinds of human tumours. The current version of the system contains almost 800 separate experiments.
In short, IntOGen is a unique and valuable resource for the cancer research community, as it makes the integration of large quantity of oncogenomic data easier, in a simple and concise way.