The promiscuity of chemical probes discovered
A new computer tool lets the interaction between small molecules and thousands of proteins be predicted to study their relationship to different diseases. The study has proven that many of these small molecules or chemical probes are not as selective as believed, but instead interact with multiple proteins, which could lead to confusion in experimental results. Understanding these interactions is key to developing more efficient and safer pharmaceuticals
Project iPIE: Testing the environmental impact of drugs

The project iPIE: Intelligence Led Assessment of Pharmaceuticals in the Environment starts on February 2015 with a kick off meeting at Barcelona Biomedical Research Park (PRBB) and the participation of the GRIB research groups of Integrative Biomedical Informatics (IBI) and PharmacoInformatics (PhI) of Institut Hospital del Mar d'Investigacions Mèdiques (IMIM) and Pompeu Fabra University (UPF).

Pura Muñoz, nominated for the La Vanguardia Science prize
For her research into ageing. UPF is the only institution to have had nominees at the five editions held to date. The general public can vote until 28 February for the most relevant research in 2014.
UPF's researchers are going to study migraine thanks to a grant from the Migraine Research Foundation
Personalized treatments for the hemiplegic migraine will be on study by José M. Fernández-Fernández, member of the Laboratory of Molecular Physiology and Channelopathies at CEXS and the principal investigator of the study.
A new and efficient method discovers switches predictive of cancer
Described in a paper published in Nucleic Acids Research, coordinated by Eduardo Eyras, ICREA researher at CEXS. A new computational method that analyzed the Cancer Genome Atlas and identifies signatures useful as predictive of the disease.
Deciphering the genetic fingerprint of the domestication of the horse
An international study involving Tomàs Marquès-Bonet, ICREA researcher at the CEXS and head of the Comparative Genomics Laboratory at the IBE (UPF-CSIC), was published in the Proceedings of the National Academy of Sciences on 15 December.
Open Call: Teaching Mentorship Programme DCEXS-UPF 2014-2015

The main objective of the Teaching Mentorship Programme (TMP) is to allow young post-doctoral researchers of the PRBB to get the basic knowledge and skills used in university teaching. This will enhance their working opportunities in academic institutions worldwide.

The mentees will be chosen after their applications to an open call performed by the DCEXS. Applications should be sent to the from the 19th of December to the 20th of January 2015, inclusive.

Roderic Guigó participates in the sequencing of the centipede genome
The scientists sequenced the genome of Strigamia maritima, a northern European centipede, as part of a study published in the journal PLOS Biology. This study improves knowledge of the evolution and diversification of the mandibulate arthropods.
INTERVIEW with Arcadi Navarro: "It's thrilling that goodwill can make achievements like establishing the EGA in Barcelona possible"
Arcadi Navarro Cuartiellas is an ICREA (Catalan Institution for Research and Advanced Studies) research professor, director of the Evolutionary Genomics Research Group at the Institute of Evolutionary Biology (established by the Spanish National Research Council and UPF), and a team leader at the Centre for Genomic Regulation (CRG). He has been in charge of the European Genome-phenome Archive (EGA) project in Barcelona since 2013.
Humans and Mice: Similar enough for studying disease and different enough to give us new clues about evolution
An international consortium including researchers from the Centre for Genome Regulation led by Roderic Guigó has presented an exhaustive description of the mouse's functional genome elements and their comparison with the human genome. The results will be published on November 20 in four articles in the journal  Nature as well as others in various different scientific publications.
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