Researchers of the UPF Neuropharmacology Laboratory show that the endocannabinoid system is a new therapeutic target to treat this rare disease, which is the most common inherited form of intellectual disability. The study is published in Nature Medicine.
In a paper published on 23 January, in the on-line edition of the Journal of Molecular Biology, researchers from the CEXS and the GRIB (UPF-IMIM) coordinated by Baldomero Oliva, head of the research group on Structural Bioinformatics, demonstrate the role played by some structural features inherent to that type of molecule (loops and domains), which make the molecular mechanisms of protein-protein interaction easier to understand.
A new anticoagulant mechanism based on the system the malaria mosquito uses to feed has been discovered
An international project with the participation of Ricardo Gutiérrez Gallego, a researcher in the Department of Experimental and Health Sciences (CEXS) and the Bioanalysis Research Group at the IMIM (Municipal Institute of Medical Research),has for the first time decoded the mechanism by which a substance called anophelin, binds to an enzyme, thrombin, which is involved in the blood clotting process.
A study on the three dimensional structure of bacterial biofilms will enable combating resistance to bactericides
Research published in the journal Proceedings of the National Academy of Sciences (PNAS), involving Jordi García Ojalvo and Pau Rué Queralt, investigators of the research group in Dynamics of Biological Systems, have discovered how the biofilms of Bacillus subtilis bacteria are organized in three dimensions.
The researchers analysed 780,000 genetic markers (SNPs) from 125 individuals of different populations in the north of Africa, taking the Neanderthal genome as a reference.
The propensity to suffer certain inflammatory diseases may depend on the levels of the expression of the ORMDL3 gene
The scientific breakthroughs in recent years in the field of genetic association have enabled the discovery of new genes involved in a great many diseases. These discoveries are fundamental in order to understand the underlying hereditary component in common diseases.
On 5th November, the prizes were awarded to the research teams that are to receive funding thanks to the money raised by the 2011 La Marató de TV3 telethon dedicated to organ and tissue regeneration and transplants.
In a large proportion of the cases observed, specifically 21%, the researchers of a study that has just been published in the journal PLoS One have found gains and/or losses of DNA to date not described or infrequently described, which may be related with foetal malformation
The Symposium will take place on September 17 and will count on international and renowned speakers on this topic.