Description

Our group try to understand how cells detect and respond to environmental changes. We have focused our studies in the characterization of the osmo-stress signal transduction pathways, especially those controlled by MAP kinases of the Hog1/p38 family, also known as the stress activated MAP kinases (SAPK). Using the S. cerevisiae yeast as a model organism as well as superior eukaryotic cells, we analyze the molecular mechanisms of cells to respond to an extracellular stimulus and which are the generated adaptation responses.  A proper adaptation to stress implies the modulation of several basic aspects of the cell biology. Among them, cell cycle and gene expression regulation.