Publicacions principals

  • Adrover MA, Zi Z, Duch A, Schaber J, González-Novo A, Jimenez J, Nadal-Ribelles M, Clotet J, Klipp E and Posas F. Time-Dependent Quantitative Multicomponent Control of the G1-S Network by the Stress-Activated Protein Kinase Hog1 upon Osmostress. Sci Signal. 2011 Sep 27;4(192):ra63.
  • Solé C, Nadal-Ribelles M, Kraft C, Peter M, Posas F and de Nadal E. Control of Ubp3 ubiquitin protease activity by the Hog1 SAPK modulates transcription upon osmostress. EMBO J. 2011 Jul 8;30(16):3274-84 

  • Klein M, Morillas M, Vendrell A, Brive L, Gebbia M, Wallace IM, Giaever G, Nislow C, Posas F and Grøtli M. Design, Synthesis and Characterization of a Highly Effective Inhibitor for Analog-Sensitive (as) Kinases.PLoS One. 2011;6(6):e20789. Epub 2011 Jun 17.

  • Pelet S, Rudolf F, Nadal-Ribelles, de Nadal, Posas F and Peter M. Transient activation of the HOG MAPK pathway regulates bimodal gene expression. Science. 2011 May 6;332(6030):732-5.  
  • Regot S, Macia J, Conde N, Furukawa K, Kjellén T, Peeters T, Hohmann S, de Nadal, Posas F and Solé R. Distributed biological computation with multicellular engineered networks. Nature. 2011 Jan 13;469(7329):207-11 
  • Ferreiro I, Barragan M, Gubern A, Ballestar E, Joaquin M and Posas F. The p38 SAPK is recruited to chromatin via its interaction with transcription factors. J Biol Chem. 2010 Aug 3
  • Warringer J, Hult M, Regot S, Posas F and Sunnerhagen P. The HOG Pathway Dictates the Short-term Translational Response after Hyperosmotic Shock. Mol Biol Cell. 2010 Jun 29
  • Schaber J, Adrover MA, Eriksson E, Pelet S, Petelenz-Kurdziel E, Klein D, Posas F, Goksör M, Peter M, Hohmann S and Klipp E. Biophysical properties of Saccharomyces cerevisae and their relationship with HOG pathway activation. Eur Biophys J. 2010 Jun 19
  • Ferreiro I, Joaquin M, Islam A, Gomez-Lopez G, Barragan M, Lombardía L, Domínguez O, Pisano DG, Lopez-Bigas N, Nebreda AR and Posas F. Whole genome analysis of p38 SAPK-mediated gene expression upon stress. BMC Genomics 2010 11:144 
  • de Nadal E and Posas F. Multilayered control of gene expression by stress-activated protein kinases. EMBO J. 2010 29 (1):4-13
  • Klopf E, Paskova L, Solé C, Mas G, Petryshyn A, Posas F, Wintersberger U, Ammerer G, Schüller C. Cooperation between the INO80 complex and histone chaperones determines adaptation of stress gene transcription in the yeast Saccharomyces cerevisae. Mol Cell Biol. 2009 Sep;29(18):4994-5007
  • Yaakov G, Duch A, García-Rubio M, Clotet J, Jimenez J, Aguilera A and Posas F. The Stress-activated Protein Kinase Hog1 Mediates S-phase Delay in Response to Osmostress. Mol Biol Cell. 29 (18):4994-5007 (2009)
  • Mas G, de Nadal E, Dechant R, Rodríguez de la Concepción ML, Logie C, Jimeno-González S, Chávez S, Ammerer G and Posas F. Recruitment of a chromatin remodelling complex by the Hog1 MAP kinase to stress genes. EMBO J. 28 (4):326-336 (2009) 
  • Zapater M, Sohrmann M, Peter M, Posas F and de Nadal E. Selective requirement for SAGA in HOG1-mediated gene expression depending on the severity of the external osmostress conditions. Mol. Cell. Biol. 27(11): 3900-3910 (2007).
  • Proft M, Mas G, de Nadal E, Vendrell A, Noriega N, Struhl K and Posas F. The stress-activated Hog1 kinase is a selective transcriptional elongation factor for genes responding to osmotic stress. Molecular Cell. 23: 241-250 (2006). 
  • Clotet J, Escoté X , Adrover MA, Yaakov G, Gari E, Aldea M, de Nadal E and Posas F. Phosphorylation of Hsl1 by Hog1 leads to a G(2) arrest essential for cell survival at high osmolarity. EMBO J. 25 (11):2338-46 (2006).  
  • Tomás-Cobos L, Casadomé L, Mas G, Sanz P and Posas F. Expression of the HXT1 low affinity glucose transporter requires the coordinated activities of the HOG and glucose signalling pathways. J Biol Chem. 2004 May 21; 279(21):22010-9.
  • de Nadal E, Zapater M, Alepuz PM, Sumoy L, Mas G and Posas F. The Hog1 MAP kinase recruits the Rpd3 histone deacetylase to activate osmoresponsive genes. Nature, 427 (6972): 370-374 (2004). 
  • Alepuz PM, De Nadal E, Zapater M, Ammerer G and Posas F. Osmostress-induced transcription by Hot1 depends on a Hog1-mediated recruitment of the RNA Pol II. EMBO J. 22: 2433-2442 (2003).
  • de Nadal E, Casadomé L and Posas F. Targeting the MEF2-Like Transcription Factor Smp1 by the Stress-Activated Hog1 Mitogen-Activated Protein Kinase. Mol. Cell. Biol. 23: 229-37 (2003). 
  • Proft M, Pascual-Ahuir A, de Nadal E, Ariño J, Serrano R and Posas F. Regulation of the Sko1 transcriptional repressor by the Hog1 MAP kinase in response to osmotic stress. EMBO J. 20: 1123-1133 (2001). 
  • Bilsland-Marchesan E, Ariño J, Saito H, Sunnerhagen P and Posas F. RCK2 kinase is a substrate for the osmotic stress-activated mitogen-activated protein kinase HOG1. Mol. Cell. Biol., 20: 3887-3895 (2000).
Last updated 27-11-2012
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